Cell Biology Antibodies 5
Anti-MYCT1 Antibody (CAB14541)
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- SKU:
- CAB14541
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-MYCT1 Antibody |
| Antibody SKU: | CAB14541 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 99-235 of human MYCT1 (NP_079383.2). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Rat spleen, Rat lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 99-235 of human MYCT1 (NP_079383.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | ASAP ISQW SSSR RSRS SYTH GLNR TGFY RHSG CERR SNLS LASL TFQR QASL EQAN SFPR KSSF RAST FHPF LQCP PLPV ETES QLVT LPSS NISP TIST SHSL SRPD YWSS NSLR VGLS TPPP PAYE SIIK AFPD S |
| Gene ID: | 80177 |
| Uniprot: | Q8N699 |
| Cellular Location: | Nucleus |
| Calculated MW: | 26kDa |
| Observed MW: | 27kDa |
| Synonyms: | MYCT1, MTLC |
| Background: |
| UniProt Protein Function: | MYCT1: May regulate certain MYC target genes, MYC seems to be a direct upstream transcriptional activator. Does not seem to significantly affect growth cell capacity. Overexpression seems to mediate many of the known phenotypic features associated with MYC, including promotion of apoptosis, alteration of morphology, enhancement of anchorage-independent growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation. Belongs to the MYCT1 family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 6q25.2 Cellular Component: nucleus |
| UniProt Code: | Q8N699 |
| NCBI GenInfo Identifier: | 156151389 |
| NCBI Gene ID: | 80177 |
| NCBI Accession: | NP_079383 |
| UniProt Secondary Accession: | Q8N699,Q8R411, |
| UniProt Related Accession: | Q8N699 |
| Molecular Weight: | 26 kDa |
| NCBI Full Name: | myc target protein 1 |
| NCBI Synonym Full Names: | myc target 1 |
| NCBI Official Symbol: | MYCT1 |
| NCBI Official Synonym Symbols: | MTLC |
| NCBI Protein Information: | myc target protein 1; myc target in myeloid cells 1; myc target in myeloid cells protein 1 |
| UniProt Protein Name: | Myc target protein 1 |
| UniProt Synonym Protein Names: | Myc target in myeloid cells protein 1 |
| UniProt Gene Name: | MYCT1 |
| UniProt Entry Name: | MYCT1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using MYCT1 antibody (CAB14541) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunofluorescence analysis of C6 cells using MYCT1 antibody (CAB14541) at dilution of 1:100. Blue: DAPI for nuclear staining. |
 | Immunofluorescence analysis of HeLa cells using MYCT1 antibody (CAB14541) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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