Anti-MVD Antibody (CAB0813)
- SKU:
- CAB0813
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- MVD
- Synonyms:
- FP17780
- Synonyms:
- MDDase
- Synonyms:
- MPD
- Synonyms:
- POROK7
- Synonyms:
- diphosphomevalonate decarboxylase
- Research Area:
- Metabolism
Description
| Product Name: | MVD Rabbit mAb |
| Product Code: | CAB0813 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | MVD, FP17780, MDDase, MPD, POROK7, diphosphomevalonate decarboxylase |
| Applications: | WB |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human MVD. |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Rat |
| Positive Samples: | HepG2, Rat brain |
| Immunogen: | A synthesized peptide derived from human MVD. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 4597 |
| Uniprot: | P53602 |
| Calculated MW: | 43kDa |
| Observed MW: | 43KDa |
| UniProt Protein Function: | MVD: Performs the first committed step in the biosynthesis of isoprenes. Belongs to the diphosphomevalonate decarboxylase family. |
| UniProt Protein Details: | Protein type:Secondary Metabolites Metabolism - terpenoid backbone biosynthesis; Lyase; EC 4.1.1.33 Chromosomal Location of Human Ortholog: 16q24.3 Cellular Component: cytosol; peroxisome Molecular Function:diphosphomevalonate decarboxylase activity; Hsp70 protein binding; protein homodimerization activity Biological Process: cholesterol biosynthetic process; dolichyl diphosphate biosynthetic process; isopentenyl diphosphate biosynthetic process, mevalonate pathway; isoprenoid biosynthetic process; positive regulation of cell proliferation |
| NCBI Summary: | The enzyme mevalonate pyrophosphate decarboxylase catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate in one of the early steps in cholesterol biosynthesis. It decarboxylates and dehydrates its substrate while hydrolyzing ATP. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P53602 |
| NCBI GenInfo Identifier: | 1706681 |
| NCBI Gene ID: | 4597 |
| NCBI Accession: | P53602.1 |
| UniProt Secondary Accession: | P53602,Q53Y65, |
| UniProt Related Accession: | P53602 |
| Molecular Weight: | 43,405 Da |
| NCBI Full Name: | Diphosphomevalonate decarboxylase |
| NCBI Synonym Full Names: | mevalonate diphosphate decarboxylase |
| NCBI Official Symbol: | MVD |
| NCBI Official Synonym Symbols: | MPD; MDDase; POROK7; FP17780 |
| NCBI Protein Information: | diphosphomevalonate decarboxylase |
| UniProt Protein Name: | Diphosphomevalonate decarboxylase |
| UniProt Synonym Protein Names: | Mevalonate (diphospho)decarboxylase; MDDase; Mevalonate pyrophosphate decarboxylase |
| UniProt Gene Name: | MVD |
| UniProt Entry Name: | MVD1_HUMAN |
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