Anti-Musashi-1 (MSI1) Antibody (CAB9122)
- SKU:
- CAB9122
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- MSI1
- Synonyms:
- musashi RNA binding protein 1
- Research Area:
- Cell Biology
Description
| Product Name: | Musashi-1 (MSI1) Rabbit mAb |
| Product Code: | CAB9122 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | MSI1, musashi RNA binding protein 1 |
| Applications: | WB, IF |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human Musashi-1 (MSI1) |
| Applications: | WB, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: | SH-SY5Y, Mouse brain |
| Immunogen: | A synthesized peptide derived from human Musashi-1 (MSI1) |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 4440 |
| Uniprot: | O43347 |
| Cellular Location: | Cytoplasm, Nucleus |
| Calculated MW: | 39kDa |
| Observed MW: | 39kDa |
| UniProt Protein Function: | Musashi-1: RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'- GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'- [GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system. Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines. Belongs to the Musashi family. |
| UniProt Protein Details: | Protein type:RNA-binding Chromosomal Location of Human Ortholog: 12q24 Molecular Function:RNA binding Biological Process: nervous system development |
| NCBI Summary: | This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas. A pseudogene for this gene is located on chromosome 11q13. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O43347 |
| NCBI GenInfo Identifier: | 51316193 |
| NCBI Gene ID: | 4440 |
| NCBI Accession: | O43347.1 |
| UniProt Secondary Accession: | O43347,Q96PU0, Q96PU1, Q96PU2, Q96PU3, |
| UniProt Related Accession: | O43347 |
| Molecular Weight: | 39,125 Da |
| NCBI Full Name: | RNA-binding protein Musashi homolog 1 |
| NCBI Synonym Full Names: | musashi RNA binding protein 1 |
| NCBI Official Symbol: | MSI1 |
| NCBI Protein Information: | RNA-binding protein Musashi homolog 1 |
| UniProt Protein Name: | RNA-binding protein Musashi homolog 1 |
| Protein Family: | RNA-binding protein |
| UniProt Gene Name: | MSI1 |
| UniProt Entry Name: | MSI1H_HUMAN |
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