Cell Biology Antibodies 13

Anti-MTMR8 Antibody (CAB17723)

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SKU:
CAB17723
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-MTMR8 Antibody
Antibody SKU:CAB17723
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 430-560 of human MTMR8 (NP_060147.2).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:U-87MG, SKOV3, HT-29
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 430-560 of human MTMR8 (NP_060147.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:HVFS CQFG NFLG NCQK DRED LRVY EKTH SVWP FLVQ RKPD FRNP LYKG FTMY GVLN PSTV PYNI QFWC GMYN RFDK GLQP KQSM LESL LEIK KQRA MLET DVHE LEKK LKVR DEPP EEIC TCSQ LGNI LSQ
Gene ID:55613
Uniprot:Q96EF0
Cellular Location:
Calculated MW:66kDa/78kDa
Observed MW:79kDa
Anti-MTMR8 Antibody (CAB17723)Western blot - MTMR8 Rabbit pAb (CAB17723)
Synonyms:MTMR8
Background:This gene encodes a member of the myotubularin-related family and is part of the MTMR6 subgroup. Family members are dual-specificity phosphatases and the encoded protein contains a phosphoinositide-binding domain (PID) and a SET-interacting domain (SID). Defects in other family members have been found in myotubular myopathic diseases. [provided by RefSeq, Mar 2010]
UniProt Protein Function:MTMR8: Phosphatase that acts on lipids with a phosphoinositol headgroup (Probable). Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Protein phosphatase, tyrosine (non-receptor); EC 3.1.3.-; Phosphatase, lipid

Chromosomal Location of Human Ortholog: Xq11.2

Cellular Component: nuclear envelope

Molecular Function:protein tyrosine phosphatase activity

NCBI Summary:This gene encodes a member of the myotubularin-related family and is part of the MTMR6 subgroup. Family members are dual-specificity phosphatases and the encoded protein contains a phosphoinositide-binding domain (PID) and a SET-interacting domain (SID). Defects in other family members have been found in myotubular myopathic diseases. [provided by RefSeq, Mar 2010]
UniProt Code:Q96EF0
NCBI GenInfo Identifier:74751838
NCBI Gene ID:55613
NCBI Accession:Q96EF0.1
UniProt Secondary Accession:Q96EF0,Q5JT99, Q9NXP6,
UniProt Related Accession:Q96EF0
Molecular Weight:704
NCBI Full Name:Myotubularin-related protein 8
NCBI Synonym Full Names:myotubularin related protein 8
NCBI Official Symbol:MTMR8  
NCBI Protein Information:myotubularin-related protein 8
UniProt Protein Name:Myotubularin-related protein 8
Protein Family:Myotubularin-related protein
UniProt Gene Name:MTMR8  
UniProt Entry Name:MTMR8_HUMAN
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