Cell Biology Antibodies 11
Anti-MTMR4 Antibody (CAB7761)
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- SKU:
- CAB7761
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-MTMR4 Antibody |
| Antibody SKU: | CAB7761 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 570-820 of human MTMR4 (NP_004678.3). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 570-820 of human MTMR4 (NP_004678.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | YLPA SSPC TLGE ENMD LYLS PVAQ SQEF SGRS LDRL PKTR SMDD LLSA CDTS SPLT RTSS DPNL NNHC QEVR VGLE PWHS NPEG SETS FVDS GVGG PQQT VGEV GLPP PLPS SQKD YLSN KPFK SHKS CSPS YKLL NTAV PREM KSNT SDPE IKVL EETK GPAP DPSA QDEL GRTL DGIG EPPE HCPE TEAV SALS KVIS NKCD GVCN FPES SQNS PTGT PQQA QPDS MLGV PSKC VLDH SLST VCNP PSA |
| Gene ID: | 9110 |
| Uniprot: | Q9NYA4 |
| Cellular Location: | Cytoplasm, Membrane, Peripheral membrane protein |
| Calculated MW: | 133kDa |
| Observed MW: | Refer to figures |
| Synonyms: | MTMR4, FYVE-DSP2, ZFYVE11 |
| Background: |
| UniProt Protein Function: | MTMR4: Dephosphorylates proteins phosphorylated on Ser, Thr, and Tyr residues and low molecular weight phosphatase substrate para-nitrophenylphosphate. Phosphorylates phosphatidylinositol 3,4,5-trisphosphate (PIP3). Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; EC 3.1.3.48; Phosphatase, lipid; Protein phosphatase, tyrosine (non-receptor); Protein phosphatase, dual-specificity Chromosomal Location of Human Ortholog: 17q22 Cellular Component: cytosol; early endosome membrane; extracellular space Molecular Function:phosphatidylinositol-3-phosphatase activity; protein binding; protein serine/threonine phosphatase activity Biological Process: negative regulation of transforming growth factor beta receptor signaling pathway; phosphatidylinositol biosynthetic process; protein amino acid dephosphorylation |
| UniProt Code: | Q9NYA4 |
| NCBI GenInfo Identifier: | 296438298 |
| NCBI Gene ID: | 9110 |
| NCBI Accession: | Q9NYA4.2 |
| UniProt Secondary Accession: | Q9NYA4,Q8IV27, Q9Y4D5, D3DTZ6, |
| UniProt Related Accession: | Q9NYA4 |
| Molecular Weight: | 133,353 Da |
| NCBI Full Name: | Myotubularin-related protein 4 |
| NCBI Synonym Full Names: | myotubularin related protein 4 |
| NCBI Official Symbol: | MTMR4 |
| NCBI Official Synonym Symbols: | ZFYVE11; FYVE-DSP2 |
| NCBI Protein Information: | myotubularin-related protein 4 |
| UniProt Protein Name: | Myotubularin-related protein 4 |
| UniProt Synonym Protein Names: | FYVE domain-containing dual specificity protein phosphatase 2; FYVE-DSP2; Zinc finger FYVE domain-containing protein 11 |
| Protein Family: | Myotubularin-related protein |
| UniProt Gene Name: | MTMR4 |
| UniProt Entry Name: | MTMR4_HUMAN |
 | Immunofluorescence analysis of A549 cells using MTMR4 antibody (CAB7761). Blue: DAPI for nuclear staining. |
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