Cell Biology Antibodies 11

Anti-MTMR4 Antibody (CAB7761)

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SKU:
CAB7761
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-MTMR4 Antibody
Antibody SKU:CAB7761
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 570-820 of human MTMR4 (NP_004678.3).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:100
Reactivity:Human, Mouse
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 570-820 of human MTMR4 (NP_004678.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:YLPA SSPC TLGE ENMD LYLS PVAQ SQEF SGRS LDRL PKTR SMDD LLSA CDTS SPLT RTSS DPNL NNHC QEVR VGLE PWHS NPEG SETS FVDS GVGG PQQT VGEV GLPP PLPS SQKD YLSN KPFK SHKS CSPS YKLL NTAV PREM KSNT SDPE IKVL EETK GPAP DPSA QDEL GRTL DGIG EPPE HCPE TEAV SALS KVIS NKCD GVCN FPES SQNS PTGT PQQA QPDS MLGV PSKC VLDH SLST VCNP PSA
Gene ID:9110
Uniprot:Q9NYA4
Cellular Location:Cytoplasm, Membrane, Peripheral membrane protein
Calculated MW:133kDa
Observed MW:Refer to figures
Synonyms:MTMR4, FYVE-DSP2, ZFYVE11
Background:
UniProt Protein Function:MTMR4: Dephosphorylates proteins phosphorylated on Ser, Thr, and Tyr residues and low molecular weight phosphatase substrate para-nitrophenylphosphate. Phosphorylates phosphatidylinositol 3,4,5-trisphosphate (PIP3). Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
UniProt Protein Details:

Protein type:Motility/polarity/chemotaxis; EC 3.1.3.48; Phosphatase, lipid; Protein phosphatase, tyrosine (non-receptor); Protein phosphatase, dual-specificity

Chromosomal Location of Human Ortholog: 17q22

Cellular Component: cytosol; early endosome membrane; extracellular space

Molecular Function:phosphatidylinositol-3-phosphatase activity; protein binding; protein serine/threonine phosphatase activity

Biological Process: negative regulation of transforming growth factor beta receptor signaling pathway; phosphatidylinositol biosynthetic process; protein amino acid dephosphorylation

UniProt Code:Q9NYA4
NCBI GenInfo Identifier:296438298
NCBI Gene ID:9110
NCBI Accession:Q9NYA4.2
UniProt Secondary Accession:Q9NYA4,Q8IV27, Q9Y4D5, D3DTZ6,
UniProt Related Accession:Q9NYA4
Molecular Weight:133,353 Da
NCBI Full Name:Myotubularin-related protein 4
NCBI Synonym Full Names:myotubularin related protein 4
NCBI Official Symbol:MTMR4  
NCBI Official Synonym Symbols:ZFYVE11; FYVE-DSP2  
NCBI Protein Information:myotubularin-related protein 4
UniProt Protein Name:Myotubularin-related protein 4
UniProt Synonym Protein Names:FYVE domain-containing dual specificity protein phosphatase 2; FYVE-DSP2; Zinc finger FYVE domain-containing protein 11
Protein Family:Myotubularin-related protein
UniProt Gene Name:MTMR4  
UniProt Entry Name:MTMR4_HUMAN
Anti-MTMR4 Antibody (CAB7761)Immunofluorescence analysis of A549 cells using MTMR4 antibody (CAB7761). Blue: DAPI for nuclear staining.
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