Cell Biology Antibodies 16
Anti-MTHFR Antibody (CAB0305)
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- SKU:
- CAB0305
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-MTHFR Antibody |
| Antibody SKU: | CAB0305 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human MTHFR (NP_005948.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | 293T |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human MTHFR (NP_005948.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MVNE ARGN SSLN PCLE GSAS SGSE SSKD SSRC STPG LDPE RHER LREK MRRR LESG DKWF SLEF FPPR TAEG AVNL ISRF DRMA AGGP LYID VTWH PAGD PGSD KETS SMMI ASTA VNYC GLET ILHM TCCR QRLE EITG HLHK AKQL GLKN IMAL RGDP IGDQ WEEE EGGF NYAV DLVK HIRS EFGD YFDI CVAG YPKG HPEA GSFE ADLK HLKE KVSA GADF IITQ LF |
| Gene ID: | 4524 |
| Uniprot: | P42898 |
| Cellular Location: | |
| Calculated MW: | 75kDa |
| Observed MW: | 80kDa |
 | Western blot - MTHFR Rabbit pAb (CAB0305) |
| Synonyms: | MTHFR |
| Background: | The protein encoded by this gene catalyzes the conversion of 5, 10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency. |
| UniProt Protein Function: | Catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. |
| NCBI Summary: | The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.[provided by RefSeq, Oct 2009] |
| UniProt Code: | P42898 |
| NCBI GenInfo Identifier: | 56405339 |
| NCBI Gene ID: | 4524 |
| NCBI Accession: | P42898.3 |
| UniProt Secondary Accession: | P42898,Q5SNW6, Q5SNW9, Q7Z6M6, Q8IU73, Q9UQR2, B2R7A6 |
| UniProt Related Accession: | P42898 |
| Molecular Weight: | 78,965 Da |
| NCBI Full Name: | Methylenetetrahydrofolate reductase |
| NCBI Synonym Full Names: | methylenetetrahydrofolate reductase |
| NCBI Official Symbol: | MTHFR |
| NCBI Protein Information: | methylenetetrahydrofolate reductase |
| UniProt Protein Name: | Methylenetetrahydrofolate reductase |
| Protein Family: | Methylenetetrahydrofolate reductase |
| UniProt Gene Name: | MTHFR |
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