Epigenetics & Nuclear Signaling Antibodies 4

Anti-MTERFD3 Antibody (CAB8518)

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SKU:
CAB8518
Product Type:
Antibody
Applications:
WB
Applications:
IHC
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Epigenetics and Nuclear Signaling

Description

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Antibody Name:Anti-MTERFD3 Antibody
Antibody SKU:CAB8518
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human MTERFD3 (NP_079474.2).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:100
Reactivity:Human, Mouse, Rat
Positive Samples:HepG2, U-251MG, NCI-H460, Mouse liver, Mouse kidney, Rat heart
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human MTERFD3 (NP_079474.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MLWK LLLR SQSC RLCS FRKM RSPP KYRP FLAC FTYT TDKQ SSKE NTRT VEKL YKCS VDIR KIRR LKGW VLLE DETY VEEI ANIL QELG ADET AVAS ILER CPEA IVCS PTAV NTQR KLWQ LVCK NEEE LIKL IEQF PESF FTIK DQEN QKLN VQFF QELG LKNV VISR LLTA APNV FHNP VEKN KQMV RILQ ESYL DVGG SEAN MKVW LLKL LSQN PFIL LNSP TAIK ETLE FLQE QGFT SFEI LQLL SK
Gene ID:80298
Uniprot:Q49AM1
Cellular Location:Mitochondrion, Mitochondrion matrix, mitochondrion nucleoid
Calculated MW:44kDa
Observed MW:38-44kDa
Synonyms:MTERF2, MTERFD3, mTERFL
Background:
UniProt Protein Function:MTERFD3: Binds promoter DNA and regulates mitochondrial transcription. Required for normal levels of transcription, both for mRNA and tRNA. Required for normal mitochondrial protein synthesis, assembly of respiratory complexes and normal mitochondrial function. Belongs to the mTERF family.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 12q24.1

Cellular Component: mitochondrial matrix

Molecular Function:protein homodimerization activity; double-stranded DNA binding

Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent

UniProt Code:Q49AM1
NCBI GenInfo Identifier:21314736
NCBI Gene ID:80298
NCBI Accession:NP_079474
UniProt Related Accession:Q49AM1
Molecular Weight:42kDa
NCBI Full Name:transcription termination factor 2, mitochondrial
NCBI Synonym Full Names:mitochondrial transcription termination factor 2
NCBI Official Symbol:MTERF2  
NCBI Official Synonym Symbols:mTERFL; MTERFD3  
NCBI Protein Information:transcription termination factor 2, mitochondrial
UniProt Protein Name:Transcription termination factor 2, mitochondrial
UniProt Synonym Protein Names:Mitochondrial transcription termination factor 2; mTERF2; mTERFL; Mitochondrial transcription termination factor-like protein; mTERF domain-containing protein 3, mitochondrial
Protein Family:Transcription termination factor
UniProt Gene Name:MTERF2  
UniProt Entry Name:MTEF2_HUMAN
Anti-MTERFD3 Polyclonal Antibody (CAB8518)Western blot analysis of extracts of various cell lines, using MTERFD3 antibody (CAB8518) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
Anti-MTERFD3 Polyclonal Antibody (CAB8518)Immunohistochemistry of paraffin-embedded mouse kidney using MTERFD3 antibody (CAB8518) at dilution of 1:100 (40x lens).
Anti-MTERFD3 Polyclonal Antibody (CAB8518)Immunohistochemistry of paraffin-embedded rat kidney using MTERFD3 antibody (CAB8518) at dilution of 1:100 (40x lens).
Anti-MTERFD3 Polyclonal Antibody (CAB8518)Immunohistochemistry of paraffin-embedded human stomach using MTERFD3 antibody (CAB8518) at dilution of 1:100 (40x lens).
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