Cell Biology Antibodies 10

Anti-MTA3 Antibody (CAB6660)

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SKU:
CAB6660
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-MTA3 Antibody
Antibody SKU:CAB6660
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 40-330 of human MTA3 (NP_065795.1).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:HeLa, HepG2, A-549
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 40-330 of human MTA3 (NP_065795.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:AKVV CFYR RRDI SNTL IMLA DKHA KEIE EESE TTVE ADLT DKQK HQLK HREL FLSR QYES LPAT HIRG KCSV ALLN ETES VLSY LDKE DTFF YSLV YDPS LKTL LADK GEIR VGPR YQAD IPEM LLEG ESDE REQS KLEV KVWD PNSP LTDR QIDQ FLVV ARAV GTFA RALD CSSS VRQP SLHM SAAA ASRD ITLF HAMD TLYR HSYD LSSA ISVL VPLG GPVL CRDE MEEW SASE ASLF EEAL EKYG KDFN DIRQ DFLP WKSL TSII EYYY MWKT TDRY VQQK RLKA AEA
Gene ID:57504
Uniprot:Q9BTC8
Cellular Location:Nucleus
Calculated MW:58kDa/67kDa
Observed MW:65kDa
Synonyms:MTA3
Background:
UniProt Protein Function:MTA3: Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Transcription factor

Chromosomal Location of Human Ortholog: 2p21

Cellular Component: nucleoplasm; intracellular membrane-bound organelle; nucleus

Molecular Function:protein binding; zinc ion binding; sequence-specific DNA binding; chromatin binding; transcription factor activity

Biological Process: establishment and/or maintenance of chromatin architecture; regulation of transcription, DNA-dependent

UniProt Code:Q9BTC8
NCBI GenInfo Identifier:29840798
NCBI Gene ID:57504
NCBI Accession:Q9BTC8.2
UniProt Secondary Accession:Q9BTC8,Q9NSP2, Q9ULF4,
UniProt Related Accession:Q9BTC8
Molecular Weight:594
NCBI Full Name:Metastasis-associated protein MTA3
NCBI Synonym Full Names:metastasis associated 1 family, member 3
NCBI Official Symbol:MTA3  
NCBI Protein Information:metastasis-associated protein MTA3; metastasis associated family, member 3; metastasis associated gene family, member 3
UniProt Protein Name:Metastasis-associated protein MTA3
Protein Family:Metastasis-associated protein
UniProt Gene Name:MTA3  
UniProt Entry Name:MTA3_HUMAN
Anti-MTA3 Antibody (CAB6660)Western blot analysis of extracts of various cell lines, using MTA3 antibody (CAB6660) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
Anti-MTA3 Antibody (CAB6660)Immunohistochemistry of paraffin-embedded rat lung using MTA3 antibody (CAB6660) at dilution of 1:100 (40x lens).
Anti-MTA3 Antibody (CAB6660)Immunohistochemistry of paraffin-embedded rat liver using MTA3 antibody (CAB6660) at dilution of 1:100 (40x lens).
Anti-MTA3 Antibody (CAB6660)Immunohistochemistry of paraffin-embedded rat brain using MTA3 antibody (CAB6660) at dilution of 1:100 (40x lens).
Anti-MTA3 Antibody (CAB6660)Immunohistochemistry of paraffin-embedded rat spleen using MTA3 antibody (CAB6660) at dilution of 1:100 (40x lens).
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