Cell Biology Antibodies 8
Anti-MTA3 Antibody (CAB2328)
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- SKU:
- CAB2328
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-MTA3 Antibody |
| Antibody SKU: | CAB2328 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 40-330 of human MTA3 (NP_065795.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | A-549 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 40-330 of human MTA3 (NP_065795.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | AKVV CFYR RRDI SNTL IMLA DKHA KEIE EESE TTVE ADLT DKQK HQLK HREL FLSR QYES LPAT HIRG KCSV ALLN ETES VLSY LDKE DTFF YSLV YDPS LKTL LADK GEIR VGPR YQAD IPEM LLEG ESDE REQS KLEV KVWD PNSP LTDR QIDQ FLVV ARAV GTFA RALD CSSS VRQP SLHM SAAA ASRD ITLF HAMD TLYR HSYD LSSA ISVL VPLG GPVL CRDE MEEW SASE ASLF EEAL EKYG KDFN DIRQ DFLP WKSL TSII EYYY MWKT TDRY VQQK RLKA AEA |
| Gene ID: | 57504 |
| Uniprot: | Q9BTC8 |
| Cellular Location: | Nucleus |
| Calculated MW: | 58kDa/67kDa |
| Observed MW: | 67kDa |
| Synonyms: | MTA3 |
| Background: |
| UniProt Protein Function: | MTA3: Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Transcription factor Chromosomal Location of Human Ortholog: 2p21 Cellular Component: nucleoplasm; intracellular membrane-bound organelle; nucleus Molecular Function:protein binding; zinc ion binding; sequence-specific DNA binding; chromatin binding; transcription factor activity Biological Process: establishment and/or maintenance of chromatin architecture; regulation of transcription, DNA-dependent |
| UniProt Code: | Q9BTC8 |
| NCBI GenInfo Identifier: | 29840798 |
| NCBI Gene ID: | 57504 |
| NCBI Accession: | Q9BTC8.2 |
| UniProt Secondary Accession: | Q9BTC8,Q9NSP2, Q9ULF4, |
| UniProt Related Accession: | Q9BTC8 |
| Molecular Weight: | 594 |
| NCBI Full Name: | Metastasis-associated protein MTA3 |
| NCBI Synonym Full Names: | metastasis associated 1 family, member 3 |
| NCBI Official Symbol: | MTA3 |
| NCBI Protein Information: | metastasis-associated protein MTA3; metastasis associated family, member 3; metastasis associated gene family, member 3 |
| UniProt Protein Name: | Metastasis-associated protein MTA3 |
| Protein Family: | Metastasis-associated protein |
| UniProt Gene Name: | MTA3 |
| UniProt Entry Name: | MTA3_HUMAN |
 | Western blot analysis of extracts of A-549 cells, using MTA3 antibody (CAB2328) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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