Anti-MT3 Antibody (CAB20541)
- SKU:
- CAB20541
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- GIF
- Synonyms:
- GIFB
- Synonyms:
- GRIF
- Synonyms:
- ZnMT3
Description
| Product Name: | MT3 Rabbit pAb |
| Product Code: | CAB20541 |
| Size: | 50uL, 100uL |
| Synonyms: | GIF, GIFB, GRIF, ZnMT3 |
| Applications: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human MT3. |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Immunogen: | Recombinant protein of human MT3. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 4504 |
| Uniprot: | P25713 |
| Calculated MW: | 6kDa |
| Observed MW: | Refer to figures |
| UniProt Protein Function: | MT3: Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro. Belongs to the metallothionein superfamily. Type 1 family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 16q13 Cellular Component: synaptic vesicle; perinuclear region of cytoplasm; cytoplasm; inclusion body; intracellular Molecular Function:antioxidant activity; protein binding; copper ion binding; zinc ion binding; caspase inhibitor activity; drug binding; cadmium ion binding; protein kinase activator activity Biological Process: positive regulation of catalytic activity; negative regulation of autophagy; removal of superoxide radicals; positive regulation of transcription, DNA-dependent; negative regulation of axon extension; negative regulation of caspase activity; positive regulation of vascular endothelial growth factor receptor signaling pathway; zinc ion homeostasis; cadmium ion homeostasis; cellular lipid catabolic process; histone modification; protein kinase B signaling cascade; negative regulation of neuron apoptosis; cholesterol catabolic process; regulation of response to food; protein stabilization; cellular zinc ion homeostasis; activation of protein kinase B; zinc ion transport; regulation of protein amino acid glycosylation; astrocyte development; leptin-mediated signaling pathway; cell proliferation; cellular metal ion homeostasis; protein import into nucleus, translocation; negative regulation of oxidoreductase activity; response to hypoxia; energy reserve metabolic process; positive regulation of protein amino acid phosphorylation; negative regulation of cell growth; negative regulation of transcription, DNA-dependent; negative regulation of apoptosis |
| UniProt Code: | P25713 |
| NCBI GenInfo Identifier: | 5174762 |
| NCBI Gene ID: | 4504 |
| NCBI Accession: | NP_005945.1 |
| UniProt Secondary Accession: | P25713,Q2V574, |
| UniProt Related Accession: | P25713 |
| Molecular Weight: | 6,927 Da |
| NCBI Full Name: | metallothionein-3 |
| NCBI Synonym Full Names: | metallothionein 3 |
| NCBI Official Symbol: | MT3 |
| NCBI Official Synonym Symbols: | GIF; GIFB; GRIF; ZnMT3 |
| NCBI Protein Information: | metallothionein-3; MT-3; MT-III; metallothionein-III; growth inhibitory factor; metallothionein 3 (growth inhibitory factor (neurotrophic)) |
| UniProt Protein Name: | Metallothionein-3 |
| UniProt Synonym Protein Names: | GIFB; GIF; Growth inhibitory factor; Metallothionein-III |
| Protein Family: | Metallothionein |
| UniProt Gene Name: | MT3 |
| UniProt Entry Name: | MT3_HUMAN |
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