Anti-MSY2 Antibody (CAB20378)
- SKU:
- CAB20378
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- DBPC
- Synonyms:
- MSY2
- Synonyms:
- CSDA3
- Synonyms:
- CONTRIN
Description
| Product Name: | MSY2 Rabbit pAb |
| Product Code: | CAB20378 |
| Size: | 50uL, 100uL |
| Synonyms: | DBPC, MSY2, CSDA3, CONTRIN |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human MSY2. |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | MCF7, SH-SY5Y, Mouse testis |
| Immunogen: | Recombinant protein of human MSY2. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 51087 |
| Uniprot: | Q9Y2T7 |
| Calculated MW: | 38kDa |
| Observed MW: | 50KDa |
| UniProt Protein Function: | YBX2: Major constituent of messenger ribonucleoprotein particles (mRNPs). Involved in the regulation of the stability and/or translation of germ cell mRNAs. Binds to Y-box consensus promoter element. Binds to full length mRNA with high affinity in a sequence-independent manner. Binds to short RNA sequences containing the consensus site 5'-UCCAUCA-3' with low affinity and limited sequence specificity. Its binding with maternal mRNAs is necessary for its cytoplasmic retention. May mark specific mRNAs (those transcribed from Y-box promoters) in the nucleus for cytoplasmic storage, thereby linking transcription and mRNA storage/translational delay. Chromosomal Location of Human Ortholog: 17p13.1 Cellular Component: nucleolus; nucleus Biological Process: spermatogenesis; transcription from RNA polymerase II promoter; translational attenuation |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a nucleic acid binding protein which is highly expressed in germ cells. The encoded protein binds to a Y-box element in the promoters of certain genes but also binds to mRNA transcribed from these genes. Pseudogenes for this gene are located on chromosome 10 and 15. [provided by RefSeq, Feb 2012] |
| UniProt Code: | Q9Y2T7 |
| NCBI GenInfo Identifier: | 116242847 |
| NCBI Gene ID: | 51087 |
| NCBI Accession: | Q9Y2T7.2 |
| UniProt Secondary Accession: | Q9Y2T7,Q8N4P0, D3DTP1 |
| UniProt Related Accession: | Q9Y2T7 |
| Molecular Weight: | 38,518 Da |
| NCBI Full Name: | Y-box-binding protein 2 |
| NCBI Synonym Full Names: | Y-box binding protein 2 |
| NCBI Official Symbol: | YBX2 |
| NCBI Official Synonym Symbols: | DBPC; MSY2; CSDA3; CONTRIN |
| NCBI Protein Information: | Y-box-binding protein 2 |
| UniProt Protein Name: | Y-box-binding protein 2 |
| UniProt Synonym Protein Names: | Contrin; DNA-binding protein C; Dbpc; Germ cell-specific Y-box-binding protein; MSY2 homolog |
| Protein Family: | Y-box-binding protein |
| UniProt Gene Name: | YBX2 |
| UniProt Entry Name: | YBOX2_HUMAN |
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