Immunology Antibodies 1
Anti-MSN Antibody (CAB12463)
- SKU:
- CAB12463
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
| Antibody Name: | Anti-MSN Antibody |
| Antibody SKU: | CAB12463 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human MSN (NP_002435.1). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: | Mouse lung, Mouse kidney |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human MSN (NP_002435.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MPKT ISVR VTTM DAEL EFAI QPNT TGKQ LFDQ VVKT IGLR EVWF FGLQ YQDT KGFS TWLK LNKK VTAQ DVRK ESPL LFKF RAKF YPED VSEE LIQD ITQR LFFL QVKE GILN DDIY CPPE TAVL LASY AVQS KYGD FNKE VHKS GYLA GDKL LPQR VLEQ HKLN KDQW EERI QVWH EEHR GMLR EDAV LEYL KIAQ DLEM YGVN YFSI KNKK GSEL WLGV DALG LNIY EQND RLTP KIGF PWSE IRNI SFND KKFV IKPI DKKA PDFV FYAP RLRI NKRI LALC MGNH ELYM RRRK PDTI |
| Gene ID: | 4478 |
| Uniprot: | P26038 |
| Cellular Location: | Apical cell membrane, Cell membrane, Cell projection, Cytoplasm, Cytoplasmic side, Peripheral membrane protein, cytoskeleton, microvillus membrane |
| Calculated MW: | 67kDa |
| Observed MW: | 72kDa |
| Synonyms: | MSN, HEL70, IMD50, moesin |
| Background: | Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement. |
| UniProt Protein Function: | Probably involved in connections of major cytoskeletal structures to the plasma membrane. May inhibit herpes simplex virus 1 infection at an early stage. |
| NCBI Summary: | Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P26038 |
| NCBI GenInfo Identifier: | 127234 |
| NCBI Gene ID: | 4478 |
| NCBI Accession: | P26038.3 |
| UniProt Secondary Accession: | P26038,P35241, P15311, P26041, P26043, P26040, O35763 P31977, |
| UniProt Related Accession: | P26038 |
| Molecular Weight: | 67,820 Da |
| NCBI Full Name: | Moesin |
| NCBI Synonym Full Names: | moesin |
| NCBI Official Symbol: | MSN |
| NCBI Official Synonym Symbols: | HEL70 |
| NCBI Protein Information: | moesin |
| UniProt Protein Name: | Moesin |
| UniProt Synonym Protein Names: | Membrane-organizing extension spike protein |
| UniProt Gene Name: | MSN |
| UniProt Entry Name: | MOES_HUMAN |
 | Western blot analysis of extracts of various cell lines, using MSN antibody (CAB12463) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. |
 | Immunohistochemistry of paraffin-embedded human liver cancer using MSN antibody (CAB12463) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse liver using MSN antibody (CAB12463) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse spleen using MSN antibody (CAB12463) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse stomach using MSN antibody (CAB12463) at dilution of 1:100 (40x lens). |
View AllClose
Related Products
