Cell Biology Antibodies 6

Anti-MS4A7 Antibody (CAB15495)

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SKU:
CAB15495
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-MS4A7 Antibody
Antibody SKU:CAB15495
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 100-200 of human MS4A7 (NP_067024.1).
Application:WB
Recommended Dilution:WB 1:200 - 1:2000
Reactivity:Mouse
Positive Samples:Mouse spleen
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 100-200 of human MS4A7 (NP_067024.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:SLSI ISGK QSTK PFDL SSLT SNAV SSVT AGAG LFLL ADSM VALR TASQ HCGS EMDY LSSL PYSE YYYP IYEI KDCL LTSV SLTG VLVV MLIF TVLE LLLA A
Gene ID:58475
Uniprot:Q9GZW8
Cellular Location:Membrane, Multi-pass membrane protein
Calculated MW:21kDa/26kDa
Observed MW:26kDa
Synonyms:MS4A7, 4SPAN2, CD20L4, CFFM4, MS4A8
Background:This gene encodes a member of the membrane-spanning 4A gene family, members of which are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns in hematopoietic cells and nonlymphoid tissues. This family member is associated with mature cellular function in the monocytic lineage, and it may be a component of a receptor complex involved in signal transduction. This gene is localized to 11q12, in a cluster of other family members. At least four alternatively spliced transcript variants encoding two distinct isoforms have been observed.
UniProt Protein Function:MS4A7: May be involved in signal transduction as a component of a multimeric receptor complex. Belongs to the MS4A family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 11q12

NCBI Summary:This gene encodes a member of the membrane-spanning 4A gene family, members of which are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns in hematopoietic cells and nonlymphoid tissues. This family member is associated with mature cellular function in the monocytic lineage, and it may be a component of a receptor complex involved in signal transduction. This gene is localized to 11q12, in a cluster of other family members. At least four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
UniProt Code:Q9GZW8
NCBI GenInfo Identifier:29611829
NCBI Gene ID:58475
NCBI Accession:Q9GZW8.1
UniProt Secondary Accession:Q9GZW8,Q6IAG8, A6NP53,
UniProt Related Accession:Q9GZW8
Molecular Weight:21,404 Da
NCBI Full Name:Membrane-spanning 4-domains subfamily A member 7
NCBI Synonym Full Names:membrane spanning 4-domains A7
NCBI Official Symbol:MS4A7  
NCBI Official Synonym Symbols:CFFM4; MS4A8; 4SPAN2; CD20L4  
NCBI Protein Information:membrane-spanning 4-domains subfamily A member 7
UniProt Protein Name:Membrane-spanning 4-domains subfamily A member 7
UniProt Synonym Protein Names:CD20 antigen-like 4; CD20/FC-epsilon-RI-beta family member 4; Four-span transmembrane protein 2
Protein Family:Membrane-spanning 4-domains subfamily
UniProt Gene Name:MS4A7  
UniProt Entry Name:MS4A7_HUMAN
Anti-MS4A7 Antibody (CAB15495)Western blot analysis of extracts of mouse spleen, using MS4A7 antibody (CAB15495) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
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