Cell Biology Antibodies 14

Anti-MS4A3 Antibody (CAB16804)

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SKU:
CAB16804

Description

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Antibody Name:Anti-MS4A3 Antibody
Antibody SKU:CAB16804
Antibody Size:20uL, 50 uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MS4A3 (NP_001026979.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MS4A3 (NP_001026979.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MASH EVDN AELG SASA HGTP GSEA GPEE LNTS VYQP IDGS PDYQ KAKL QVLG FCSS GTLS VVAG IKPT RTWI QNSF GMNI ASAT IALV GTAF LSLN IAVN
Gene ID:932
Uniprot:Q96HJ5
Cellular Location:
Calculated MW:
Observed MW:Refer to figures
Synonyms:MS4A3, CD20L, HTM4
Background:This gene encodes a member of the membrane-spanning 4A gene family. Members of this protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member likely plays a role in signal transduction and may function as a subunit associated with receptor complexes. The gene encoding this protein is localized to 11q12, among a cluster of related family members. Alternative splicing may result in multiple transcript variants; however, not all variants have been fully described.
UniProt Protein Function:MS4A3: Hematopoietic modulator for the G1-S cell cycle transition. Modulates the level of phosphorylation of cyclin- dependent kinase 2 (CDK2) through its direct binding to cyclin- dependent kinase inhibitor 3 (CDKN3/KAP). Belongs to the MS4A family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q12.1

Molecular Function:protein binding

NCBI Summary:This gene encodes a member of the membrane-spanning 4A gene family. Members of this protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member likely plays a role in signal transduction and may function as a subunit associated with receptor complexes. The gene encoding this protein is localized to 11q12, among a cluster of related family members. Alternative splicing may result in multiple transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]
UniProt Code:Q96HJ5
NCBI GenInfo Identifier:29611825
NCBI Gene ID:932
NCBI Accession:Q96HJ5.1
UniProt Secondary Accession:Q96HJ5,Q8NHW2, A8MTP8,
UniProt Related Accession:Q96HJ5
Molecular Weight:9,625 Da
NCBI Full Name:Membrane-spanning 4-domains subfamily A member 3
NCBI Synonym Full Names:membrane spanning 4-domains A3
NCBI Official Symbol:MS4A3  
NCBI Official Synonym Symbols:HTM4; CD20L  
NCBI Protein Information:membrane-spanning 4-domains subfamily A member 3
UniProt Protein Name:Membrane-spanning 4-domains subfamily A member 3
UniProt Synonym Protein Names:CD20 antigen-like protein; Hematopoietic-specific transmembrane protein 4; HTm4
Protein Family:Membrane-spanning 4-domains subfamily
UniProt Gene Name:MS4A3  
UniProt Entry Name:MS4A3_HUMAN
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Additional Information

Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
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