Cell Biology Antibodies 13
Anti-MRPS7 Antibody (CAB17150)
- SKU:
- CAB17150
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-MRPS7 Antibody |
| Antibody SKU: | CAB17150 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 110-190 of human MRPS7 (NP_057055.2). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HepG2, A-549, HT-29, Mouse liver, Mouse kidney, Rat liver, Rat kidney |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 110-190 of human MRPS7 (NP_057055.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | LMIQ TLEA VKRK QFEK YHAA SAEE QATI ERNP YTIF HQAL KNCE PMIG LVPI LKGG RFYQ VPVP LPDR RRRF LAMK WMIT E |
| Gene ID: | 51081 |
| Uniprot: | Q9Y2R9 |
| Cellular Location: | |
| Calculated MW: | 28kDa |
| Observed MW: | 28kDa |
| Synonyms: | MRPS7, MRP-S, MRP-S7, RP-S7, RPMS7, S7mt, bMRP27a |
| Background: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. In the prokaryotic ribosome, the comparable protein is thought to play an essential role in organizing the 3' domain of the 16 S rRNA in the vicinity of the P- and A-sites. Pseudogenes corresponding to this gene are found on chromosomes 8p and 12p. |
| NCBI Summary: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. In the prokaryotic ribosome, the comparable protein is thought to play an essential role in organizing the 3' domain of the 16 S rRNA in the vicinity of the P- and A-sites. Pseudogenes corresponding to this gene are found on chromosomes 8p and 12p. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9Y2R9 |
| NCBI GenInfo Identifier: | 186928852 |
| NCBI Gene ID: | 51081 |
| NCBI Accession: | NP_057055.2 |
| UniProt Secondary Accession: | Q9Y2R9,Q53GD6, B2R9N5, |
| UniProt Related Accession: | Q9Y2R9 |
| Molecular Weight: | 28,134 Da |
| NCBI Full Name: | 28S ribosomal protein S7, mitochondrial |
| NCBI Synonym Full Names: | mitochondrial ribosomal protein S7 |
| NCBI Official Symbol: | MRPS7 |
| NCBI Official Synonym Symbols: | S7mt; MRP-S; RP-S7; RPMS7; MRP-S7; COXPD34; bMRP27a |
| NCBI Protein Information: | 28S ribosomal protein S7, mitochondrial |
| UniProt Protein Name: | 28S ribosomal protein S7, mitochondrial |
| UniProt Synonym Protein Names: | Mitochondrial small ribosomal subunit protein uS7m |
| Protein Family: | Serine/threonine-protein kinase tousled |
| UniProt Gene Name: | MRPS7 |
