Cell Biology Antibodies 13
Anti-MRPS7 Antibody (CAB17150)
- SKU:
- CAB17150
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Antibody Name: | Anti-MRPS7 Antibody |
Antibody SKU: | CAB17150 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB IF |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 110-190 of human MRPS7 (NP_057055.2). |
Application: | WB IF |
Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | HepG2, A-549, HT-29, Mouse liver, Mouse kidney, Rat liver, Rat kidney |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 110-190 of human MRPS7 (NP_057055.2). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | LMIQ TLEA VKRK QFEK YHAA SAEE QATI ERNP YTIF HQAL KNCE PMIG LVPI LKGG RFYQ VPVP LPDR RRRF LAMK WMIT E |
Gene ID: | 51081 |
Uniprot: | Q9Y2R9 |
Cellular Location: | |
Calculated MW: | 28kDa |
Observed MW: | 28kDa |
Synonyms: | MRPS7, MRP-S, MRP-S7, RP-S7, RPMS7, S7mt, bMRP27a |
Background: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. In the prokaryotic ribosome, the comparable protein is thought to play an essential role in organizing the 3' domain of the 16 S rRNA in the vicinity of the P- and A-sites. Pseudogenes corresponding to this gene are found on chromosomes 8p and 12p. |
NCBI Summary: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. In the prokaryotic ribosome, the comparable protein is thought to play an essential role in organizing the 3' domain of the 16 S rRNA in the vicinity of the P- and A-sites. Pseudogenes corresponding to this gene are found on chromosomes 8p and 12p. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9Y2R9 |
NCBI GenInfo Identifier: | 186928852 |
NCBI Gene ID: | 51081 |
NCBI Accession: | NP_057055.2 |
UniProt Secondary Accession: | Q9Y2R9,Q53GD6, B2R9N5, |
UniProt Related Accession: | Q9Y2R9 |
Molecular Weight: | 28,134 Da |
NCBI Full Name: | 28S ribosomal protein S7, mitochondrial |
NCBI Synonym Full Names: | mitochondrial ribosomal protein S7 |
NCBI Official Symbol: | MRPS7 |
NCBI Official Synonym Symbols: | S7mt; MRP-S; RP-S7; RPMS7; MRP-S7; COXPD34; bMRP27a |
NCBI Protein Information: | 28S ribosomal protein S7, mitochondrial |
UniProt Protein Name: | 28S ribosomal protein S7, mitochondrial |
UniProt Synonym Protein Names: | Mitochondrial small ribosomal subunit protein uS7m |
Protein Family: | Serine/threonine-protein kinase tousled |
UniProt Gene Name: | MRPS7 |