Cell Biology Antibodies 17

Anti-MRPS17 Antibody (CAB18458)

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SKU:
CAB18458
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-MRPS17 Antibody
Antibody SKU:CAB18458
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant protein of human MRPS17.
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:
Immunogen:Recombinant protein of human MRPS17.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:51373
Uniprot:Q9Y2R5
Cellular Location:
Calculated MW:
Observed MW:Refer to figures
Synonyms:HSPC011, MRP-S17, RPMS17, S17mt, MRPS17
Background:
UniProt Protein Function:MRPS17: a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S17P family. The encoded protein is moderately conserved between human mitochondrial and prokaryotic ribosomal proteins. Pseudogenes corresponding to this gene are found on chromosomes 1p, 3p, 6q, 14p, 18q, and Xq. [provided by RefSeq, Jul 2008]
UniProt Protein Details:

Protein type:Mitochondrial; Translation; Ribosomal

Chromosomal Location of Human Ortholog: 7p11

Cellular Component: mitochondrial inner membrane; mitochondrial small ribosomal subunit

Molecular Function:rRNA binding; structural constituent of ribosome

Biological Process: mitochondrial translation; organelle organization and biogenesis; translation

NCBI Summary:Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S17P family. The encoded protein is moderately conserved between human mitochondrial and prokaryotic ribosomal proteins. Pseudogenes corresponding to this gene are found on chromosomes 1p, 3p, 6q, 14p, 18q, and Xq. [provided by RefSeq, Jul 2008]
UniProt Code:Q9Y2R5
NCBI GenInfo Identifier:13633951
NCBI Gene ID:51373
NCBI Accession:Q9Y2R5.1
UniProt Secondary Accession:Q9Y2R5,Q86X15,
UniProt Related Accession:Q9Y2R5
Molecular Weight:14,502 Da
NCBI Full Name:28S ribosomal protein S17, mitochondrial
NCBI Synonym Full Names:mitochondrial ribosomal protein S17
NCBI Official Symbol:MRPS17  
NCBI Official Synonym Symbols:S17mt; RPMS17; HSPC011; MRP-S17  
NCBI Protein Information:28S ribosomal protein S17, mitochondrial
UniProt Protein Name:28S ribosomal protein S17, mitochondrial
Protein Family:37S ribosomal protein
UniProt Gene Name:MRPS17  
UniProt Entry Name:RT17_HUMAN
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