UniProt Protein Function: | |
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NCBI Summary: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that contains a high level of sequence similarity with ribosomal protein S11P family members. A pseudogene corresponding to this gene is found on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2016] |
UniProt Code: | P82912 |
NCBI GenInfo Identifier: | 21263985 |
NCBI Gene ID: | 64963 |
NCBI Accession: | P82912.2 |
UniProt Secondary Accession: | P82912,Q969D7, Q96GI3, Q9BYC3, B2RD52 |
UniProt Related Accession: | P82912 |
Molecular Weight: | 16,904 Da |
NCBI Full Name: | 28S ribosomal protein S11, mitochondrial |
NCBI Synonym Full Names: | mitochondrial ribosomal protein S11 |
NCBI Official Symbol: | MRPS11 |
NCBI Official Synonym Symbols: | HCC-2; S11mt; MRP-S11 |
NCBI Protein Information: | 28S ribosomal protein S11, mitochondrial |
UniProt Protein Name: | 28S ribosomal protein S11, mitochondrial |
UniProt Synonym Protein Names: | Cervical cancer proto-oncogene 2 protein; HCC-2 |
Protein Family: | 28S ribosomal protein |
UniProt Gene Name: | MRPS11 |
UniProt Entry Name: | RT11_HUMAN |