Cell Biology Antibodies 18

Anti-MRPL55 Antibody (CAB18242)

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SKU:
CAB18242
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-MRPL55 Antibody
Antibody SKU:CAB18242
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant protein of human MRPL55.
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:MCF7
Immunogen:Recombinant protein of human MRPL55.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:128308
Uniprot:Q7Z7F7
Cellular Location:
Calculated MW:15kDa
Observed MW:15kDa
Anti-MRPL55 Antibody (CAB18242)Western blot - MRPL55 Rabbit pAb (CAB18242)
Synonyms:L55nt, MRP-L55, AAVG5835, PRO19675, MRPL55
Background:Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Multiple transcript variants encoding two different isoforms were identified through sequence analysis.
UniProt Protein Function:MRPL55: 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Mitochondrial

Chromosomal Location of Human Ortholog: 1q42.13

Cellular Component: mitochondrial inner membrane; mitochondrial large ribosomal subunit

Molecular Function:structural constituent of ribosome

Biological Process: mitochondrial translation; organelle organization and biogenesis; translation

NCBI Summary:Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Multiple transcript variants encoding two different isoforms were identified through sequence analysis. [provided by RefSeq, Jul 2008]
UniProt Code:Q7Z7F7
NCBI GenInfo Identifier:31563352
NCBI Gene ID:128308
NCBI Accession:NP_852106.1
UniProt Secondary Accession:Q7Z7F7,Q5TBY3, Q5TBY6, Q6UWI8,
UniProt Related Accession:Q7Z7F7
Molecular Weight:18,903 Da
NCBI Full Name:39S ribosomal protein L55, mitochondrial isoform a
NCBI Synonym Full Names:mitochondrial ribosomal protein L55
NCBI Official Symbol:MRPL55  
NCBI Official Synonym Symbols:L55nt; MRP-L55; AAVG5835; PRO19675  
NCBI Protein Information:39S ribosomal protein L55, mitochondrial
UniProt Protein Name:39S ribosomal protein L55, mitochondrial
Protein Family:39S ribosomal protein
UniProt Gene Name:MRPL55  
UniProt Entry Name:RM55_HUMAN
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