Name: Anti-MRPL51 Antibody (CAB15838)
Brand: Epigenetics & Nuclear Signaling Antibodies 2
SKU: CAB15838
Availability: OutOfStock

Antibody Name:	Anti-MRPL51 Antibody
Antibody SKU:	CAB15838
Antibody Size:	20uL, 50uL, 100uL
Application:	WB
Reactivity:	Mouse, Rat
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-128 of human MRPL51 (NP_057581.2).

Application:	WB
Recommended Dilution:	WB 1:500 - 1:2000
Reactivity:	Mouse, Rat
Positive Samples:	Mouse kidney, Rat heart, Rat kidney

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-128 of human MRPL51 (NP_057581.2).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	MAGN LLSG AGRR LWDW VPLA CRSF SLGV PRLI GIRL TLPP PKVV DRWN EKRA MFGV YDNI GILG NFEK HPKE LIRG PIWL RGWK GNEL QRCI RKRK MVGS RMFA DDLH NLNK RIRY LYKH FNRH GKFR
Gene ID:	51258
Uniprot:	Q4U2R6
Cellular Location:	Mitochondrion
Calculated MW:	15kDa
Observed MW:	14kDa

Synonyms:

MRPL51, CDA09, HSPC241, MRP64, bMRP64

Background:

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 4p and 21q.

UniProt Protein Function:	MRPL51: Component of the mitochondrial ribosome large subunit (39S) which comprises a 16S rRNA and about 50 distinct proteins.
UniProt Protein Details:	Protein type:Mitochondrial Chromosomal Location of Human Ortholog: 12p13.3-p13.1 Cellular Component: mitochondrial inner membrane; mitochondrial large ribosomal subunit; mitochondrial ribosome Molecular Function:protein binding; structural constituent of ribosome Biological Process: mitochondrial translation; organelle organization and biogenesis; translation
NCBI Summary:	Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 4p and 21q. [provided by RefSeq, Jul 2008]
UniProt Code:	Q4U2R6
NCBI GenInfo Identifier:	74762954
NCBI Gene ID:	51258
NCBI Accession:	Q4U2R6.1
UniProt Secondary Accession:	Q4U2R6,Q96Q57, Q9BQ36, Q9P0N7,
UniProt Related Accession:	Q4U2R6
Molecular Weight:	15,095 Da
NCBI Full Name:	39S ribosomal protein L51, mitochondrial
NCBI Synonym Full Names:	mitochondrial ribosomal protein L51
NCBI Official Symbol:	MRPL51
NCBI Official Synonym Symbols:	CDA09; MRP64; bMRP64; HSPC241
NCBI Protein Information:	39S ribosomal protein L51, mitochondrial
UniProt Protein Name:	39S ribosomal protein L51, mitochondrial
UniProt Synonym Protein Names:	bMRP-64; bMRP64
Protein Family:	39S ribosomal protein
UniProt Gene Name:	MRPL51
UniProt Entry Name:	RM51_HUMAN

Western blot analysis of extracts of various cell lines, using MRPL51 antibody (CAB15838) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.

Antibodies

MRPL51 Antibody (PACO02960)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)