Cell Biology Antibodies 15

Anti-MRPL43 Antibody (CAB17793)

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SKU:
CAB17793
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-MRPL43 Antibody
Antibody SKU:CAB17793
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 80-155 of human MRPL43 (NP_789762.1).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:A-549, PC-3, 293T
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 80-155 of human MRPL43 (NP_789762.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:LNGA VREE SIHC KSVE EIST LVQK LADQ SGLD VIRI RKPF HTDN PSIQ GQWH PFTN KPTT FRGL RPRE VQDP APAQ
Gene ID:84545
Uniprot:Q8N983
Cellular Location:
Calculated MW:
Observed MW:23kDa
Anti-MRPL43 Antibody (CAB17793)Western blot - MRPL43 Polyclonal Antibody (CAB17793)
Synonyms:L43mt, MRP-L43, bMRP36a, MRPL43
Background:Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene and the gene for a semaphorin class 4 protein (SEMA4G) overlap at map location 10q24.31 and are transcribed in opposite directions. Sequence analysis identified multiple transcript variants encoding at least four different protein isoforms. [provided by RefSeq, Jul 2008]
NCBI Summary:Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene and the gene for a semaphorin class 4 protein (SEMA4G) overlap at map location 10q24.31 and are transcribed in opposite directions. Sequence analysis identified multiple transcript variants encoding at least four different protein isoforms. [provided by RefSeq, Jul 2008]
UniProt Code:Q8N983
NCBI GenInfo Identifier:817477813
NCBI Gene ID:84545
NCBI Accession:NP_001295325.1
UniProt Secondary Accession:Q8N983,Q5JW06, Q7Z719, Q7Z7H6, Q86XN1, Q9BYC7, B1AL06 B1AL07, B1AL09, B1AL10, C9J5Q3, D3DR71,
UniProt Related Accession:Q8N983
Molecular Weight:23
NCBI Full Name:39S ribosomal protein L43, mitochondrial isoform e
NCBI Synonym Full Names:mitochondrial ribosomal protein L43
NCBI Official Symbol:MRPL43  
NCBI Official Synonym Symbols:L43mt; MRP-L43; bMRP36a  
NCBI Protein Information:39S ribosomal protein L43, mitochondrial
UniProt Protein Name:39S ribosomal protein L43, mitochondrial
UniProt Synonym Protein Names:Mitochondrial large ribosomal subunit protein mL43
UniProt Gene Name:MRPL43  
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