Cell Biology Antibodies 9

Anti-MRPL24 Antibody (CAB4967)

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SKU:
CAB4967
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
MRPL24
Synonyms:
L24mt
Synonyms:
MRP-L18
Synonyms:
MRP-L24
Research Area:
Cell Biology

Description

Product Name:MRPL24 Rabbit pAb
Product Code:CAB4967
Size:20uL, 50uL, 100uL
Synonyms:MRPL24, L24mt, MRP-L18, MRP-L24
Applications:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-216 of human MRPL24 (NP_078816.2).
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:Jurkat, SKOV3, MCF7, Mouse heart, Rat testis, Rat kidney, Rat liver
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-216 of human MRPL24 (NP_078816.2).
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MRLS ALLA LASK VTLP PHYR YGMS PPGS VADK RKNP PWIR RRPV VVEP ISDE DWYL FCGD TVEI LEGK DAGK QGKV VQVI RQRN WVVV GGLN THYR YIGK TMDY RGTM IPSE APLL HRQV KLVD PMDR KPTE IEWR FTEA GERV RVST RSGR IIPK PEFP RADG IVPE TWID GPKD TSVE DALE RTYV PCLK TLQE EVME AMGI KETR KYKK VYWY
Gene ID:79590
Uniprot:Q96A35
Cellular Location:Mitochondrion
Calculated MW:24kDa
Observed MW:25kDa
UniProt Protein Function:MRPL24: a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which is more than twice the size of its E.coli counterpart (EcoL24). Sequence analysis identified two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008]
UniProt Protein Details:

Protein type:Translation; Mitochondrial; Ribosomal

Chromosomal Location of Human Ortholog: 1q23.1

Cellular Component: mitochondrial inner membrane; ribosome

Molecular Function:structural constituent of ribosome

Biological Process: mitochondrial translation; organelle organization and biogenesis

NCBI Summary:Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which is more than twice the size of its E.coli counterpart (EcoL24). Sequence analysis identified two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008]
UniProt Code:Q96A35
NCBI GenInfo Identifier:74751733
NCBI Gene ID:79590
NCBI Accession:Q96A35.1
UniProt Secondary Accession:Q96A35,Q53G65, Q53HT0, Q5SYZ9, Q5SZ00, Q5SZ02, Q96Q70 Q9H7G3, D3DVC8,
UniProt Related Accession:Q96A35
Molecular Weight:216
NCBI Full Name:39S ribosomal protein L24, mitochondrial
NCBI Synonym Full Names:mitochondrial ribosomal protein L24
NCBI Official Symbol:MRPL24  
NCBI Official Synonym Symbols:L24mt; MRP-L18; MRP-L24  
NCBI Protein Information:39S ribosomal protein L24, mitochondrial
UniProt Protein Name:39S ribosomal protein L24, mitochondrial
Protein Family:39S ribosomal protein
UniProt Gene Name:MRPL24  
UniProt Entry Name:RM24_HUMAN
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