Cell Biology Antibodies 9
Anti-MRPL1 Antibody (CAB4947)
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- SKU:
- CAB4947
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- MRPL1
- Synonyms:
- BM022
- Synonyms:
- L1MT
- Synonyms:
- MRP-L1
- Research Area:
- Cell Biology
Description
| Product Name: | MRPL1 Rabbit pAb |
| Product Code: | CAB4947 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | MRPL1, BM022, L1MT, MRP-L1 |
| Applications: | WB, IHC |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 51-325 of human MRPL1 (NP_064621.3). |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:20 - 1:200 |
| Reactivity: | Human, Rat |
| Positive Samples: | A-431, MCF7, HeLa, Jurkat |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 51-325 of human MRPL1 (NP_064621.3). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | KKTK KGAK EKTP DEKK DEIE KIKA YPYM EGEP EDDV YLKR LYPR QIYE VEKA VHLL KKFQ ILDF TSPK QSVY LDLT LDMA LGKK KNVE PFTS VLSL PYPF ASEI NKVA VFTE NASE VKIA EENG AAFA GGTS LIQK IWDD EIVA DFYV AVPE IMPE LNRL RKKL NKKY PKLS RNSI GRDI PKML ELFK NGHE IKVD EERE NFLQ TKIA TLDM SSDQ IAAN LQAV INEV CRHR PLNL GPFV VRAF LRSS TSEG LLLK IDPL LPKE VKNE ESEK EDA |
| Gene ID: | 65008 |
| Uniprot: | Q9BYD6 |
| Cellular Location: | Mitochondrion |
| Calculated MW: | 36kDa |
| Observed MW: | 37kDa |
| UniProt Protein Function: | MRPL1: a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L1 ribosomal protein family. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:RNA-binding; Mitochondrial Chromosomal Location of Human Ortholog: 4q21.1 Cellular Component: nucleoplasm; mitochondrion; mitochondrial inner membrane; large ribosomal subunit Molecular Function:structural constituent of ribosome Biological Process: mitochondrial translation; organelle organization and biogenesis |
| NCBI Summary: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L1 ribosomal protein family. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9BYD6 |
| NCBI GenInfo Identifier: | 239938694 |
| NCBI Gene ID: | 65008 |
| NCBI Accession: | Q9BYD6.2 |
| UniProt Secondary Accession: | Q9BYD6,Q4W5B8, Q6IAG4, Q96BW3, Q9H793, Q9NRL5, A6NG03 |
| UniProt Related Accession: | Q9BYD6 |
| Molecular Weight: | 325 |
| NCBI Full Name: | 39S ribosomal protein L1, mitochondrial |
| NCBI Synonym Full Names: | mitochondrial ribosomal protein L1 |
| NCBI Official Symbol: | MRPL1 |
| NCBI Official Synonym Symbols: | L1MT; BM022; MRP-L1 |
| NCBI Protein Information: | 39S ribosomal protein L1, mitochondrial |
| UniProt Protein Name: | 39S ribosomal protein L1, mitochondrial |
| Protein Family: | 39S ribosomal protein |
| UniProt Gene Name: | MRPL1 |
| UniProt Entry Name: | RM01_HUMAN |
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