Cell Biology Antibodies 6
Anti-MPRIP Antibody (CAB15409)
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- SKU:
- CAB15409
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-MPRIP Antibody |
| Antibody SKU: | CAB15409 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human MPRIP (NP_055949.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:200 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human MPRIP (NP_055949.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MSAA KENP CRKF QANI FNKS KCQN CFKP RESH LLND EDLT QAKP IYGG WLLL APDG TDFD NPVH RSRK WQRR FFIL YEHG LLRY ALDE MPTT LPQG TINM NQCT DVVD GEGR TGQK FSLC ILTP EKEH FIRA ETKE IVSG WLEM LMVY PRTN KQNQ KKKR KVEP PTPQ EPGP AKVA VTSS SSSS SSSS SIPS AEKV PTTK STLW QEEM RTKD QPDG SSLS PAQS PSQS QPPA ASSL REPG LESK EEES AMSS DRMD CGRK VRVE SGYF SLEK TKQD LKAE EQQL PPPL SPPS PSTP NHRR SQVI EKFE AL |
| Gene ID: | 23164 |
| Uniprot: | Q6WCQ1 |
| Cellular Location: | Cytoplasm, cytoskeleton |
| Calculated MW: | 114kDa/116kDa/118kDa |
| Observed MW: | Refer to figures |
| Synonyms: | MPRIP, M-RIP, MRIP, RHOIP3, RIP3, p116Rip |
| Background: |
| UniProt Protein Function: | Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells. |
| UniProt Code: | Q6WCQ1 |
| NCBI GenInfo Identifier: | 50980307 |
| NCBI Gene ID: | 23164 |
| NCBI Accession: | NP_055949.2 |
| UniProt Secondary Accession: | Q6WCQ1,Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40 |
| UniProt Related Accession: | Q6WCQ1 |
| Molecular Weight: | 57kDa |
| NCBI Full Name: | myosin phosphatase Rho-interacting protein isoform 1 |
| NCBI Synonym Full Names: | myosin phosphatase Rho interacting protein |
| NCBI Official Symbol: | MPRIP |
| NCBI Official Synonym Symbols: | MRIP; RIP3; M-RIP; RHOIP3; p116Rip |
| NCBI Protein Information: | myosin phosphatase Rho-interacting protein |
| UniProt Protein Name: | Myosin phosphatase Rho-interacting protein |
| UniProt Synonym Protein Names: | Rho-interacting protein 3; RIP3; p116Rip |
| Protein Family: | Putative zinc metalloprotease |
| UniProt Gene Name: | MPRIP |
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