Anti-MOV10 Antibody (CAB7227)
- SKU:
- CAB7227
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- fSAP113
- Synonyms:
- gb110
- Research Area:
- Immunology
Description
| Product Name: | MOV10 Rabbit mAb |
| Product Code: | CAB7227 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | fSAP113, gb110 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human MOV10 |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U2OS, HepG2, NIH/3T3, U-87MG, Mouse liver, Rat kidney |
| Immunogen: | A synthesized peptide derived from human MOV10 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 4343 |
| Uniprot: | Q9HCE1 |
| Cellular Location: | Cytoplasm, P-body |
| Calculated MW: | 114kDa |
| Observed MW: | 114kDa |
| UniProt Protein Function: | MOV10: Probable RNA helicase. Required for RNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA- mediated cleavage of complementary mRNAs by RISC. Also required for RNA-directed transcription and replication of the human hepatitis delta virus (HDV). Interacts with small capped HDV RNAs derived from genomic hairpin structures that mark the initiation sites of RNA-dependent HDV RNA transcription. Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:RNA-binding; RNA processing; Helicase; EC 3.6.4.13; Spliceosome Chromosomal Location of Human Ortholog: 1p13.2 Cellular Component: extracellular space; cytosol Molecular Function:protein binding; helicase activity; ATP binding Biological Process: epidermal growth factor receptor signaling pathway; Notch signaling pathway; fibroblast growth factor receptor signaling pathway; phosphoinositide-mediated signaling; transcription, DNA-dependent; regulation of transcription, DNA-dependent; nerve growth factor receptor signaling pathway; miRNA-mediated gene silencing, mRNA cleavage; innate immune response |
| UniProt Code: | Q9HCE1 |
| NCBI GenInfo Identifier: | 24638063 |
| NCBI Gene ID: | 4343 |
| NCBI Accession: | Q9HCE1.2 |
| UniProt Related Accession: | Q9HCE1 |
| Molecular Weight: | |
| NCBI Full Name: | Helicase MOV-10 |
| NCBI Synonym Full Names: | Mov10 RISC complex RNA helicase |
| NCBI Official Symbol: | MOV10 |
| NCBI Official Synonym Symbols: | gb110; fSAP113 |
| NCBI Protein Information: | helicase MOV-10; putative helicase MOV-10 |
| UniProt Protein Name: | Putative helicase MOV-10 |
| UniProt Synonym Protein Names: | Moloney leukemia virus 10 protein |
| Protein Family: | Putative helicase |
| UniProt Gene Name: | MOV10 |
| UniProt Entry Name: | MOV10_HUMAN |
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