Anti-Mouse IL-1α In Vivo Antibody - Low Endotoxin
- SKU:
- IVMB0005
- Product Type:
- In Vivo Monoclonal Antibody
- Clone:
- ALF-161
- Protein:
- Interleukin-1 Alpha
- Isotype:
- Armenian Hamster IgG1
- Reactivity:
- Mouse
- Synonyms:
- Hematopoietin-1
- Synonyms:
- Lymphocyte-activating factor (LAF)
- Synonyms:
- Endogenous Pyrogen (EP)
- Synonyms:
- Leukocyte Endogenous Mediator (LEM)
- Synonyms:
- Mononuclear Cell Factor (MCF)
- Research Area:
- Cytokines, Chemokines & Receptors
- Endotoxin Level:
- Low Endotoxin
- Host Species:
- Armenian Hamster
- Applications:
- Neutralizing
- Applications:
- WB
Description
system_update_altTechnical Datasheet
| Product Name: | Anti-Mouse IL-1α In Vivo Antibody - Low Endotoxin |
| Product Code: | IVMB0005 |
| Size: | 1mg, 5mg, 25mg, 50mg, 100mg |
| Clone: | ALF-161 |
| Protein: | Interleukin-1 Alpha |
| Product Type: | Monoclonal Antibody |
| Synonyms: | Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF) |
| Isotype: | Armenian Hamster IgG1 |
| Reactivity: | Mouse |
| Immunogen: | Recombinant mouse IL-1α |
| Applications: | N, WB |
| Formulation: | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Endotoxin Level: | < 1.0 EU/mg as determined by the LAL method |
| Purity: | ≥95% monomer by analytical SEC >95% by SDS Page |
| Preparation: | Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. |
| Storage and Handling: | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
| Applications: | N, WB |
| Reactivity: | Mouse |
| Host Species: | Armenian Hamster |
| Specificity: | Anti-Mouse IL-1α recognizes Mouse IL-1α. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
| Immunogen: | Recombinant mouse IL-1α |
| Concentration: | ≥ 5.0 mg/ml |
| Endotoxin Level: | < 1.0 EU/mg as determined by the LAL method |
| Purity: | ≥95% monomer by analytical SEC >95% by SDS Page |
| Formulation: | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Preparation: | Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. |
| Storage and Handling: | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
Mouse IL-1alpha is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1beta is a secreted cytokine, IL-1alpha is predominantly a cell-associated cytokine.
| Technical Datasheet: | View |
| Protein: | Interleukin-1 Alpha |
| Research Area: | Immunology, Innate Immunity |
Meet the team!
Shane Costigan
Territory Manager & Team Lead
Abdul Khadim
Sales Executive
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