Anti-Mouse CD226 (DNAM-1) In Vivo Antibody - Low Endotoxin
- SKU:
- IVMB0270
- Product Type:
- In Vivo Monoclonal Antibody
- Clone:
- 480.1
- Protein:
- DNAM-1
- Isotype:
- IgG2a k
- Reactivity:
- Mouse
- Synonyms:
- DNAX Accessory Molecule 1
- Synonyms:
- CD226
- Synonyms:
- DNAM1
- Synonyms:
- PTA1
- Synonyms:
- TLiSA1
- Research Area:
- Immunology
- Endotoxin Level:
- Low Endotoxin
- Host Species:
- Rat
- Applications:
- FC
- Applications:
- In Vivo
Description
| Product Name: | Anti-Mouse CD226 (DNAM-1) In Vivo Antibody - Low Endotoxin |
| Product Code: | IVMB0270 |
| Size: | 1 mg, 5 mg, 25 mg, 50 mg, 100 mg |
| Clone: | 480.1 |
| Protein: | DNAM-1 |
| Product Type: | Monoclonal Antibody |
| Synonyms: | DNAX Accessory Molecule 1, CD226, DNAM1, PTA1, TLiSA1 |
| Isotype: | IgG2a k |
| Reactivity: | Mouse |
| Applications: | FC, In Vivo |
| Formulation: | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration. |
| Endotoxin Level: | <1.0 EU/µg as determined by the LAL method |
| Purity: | ≥95% monomer by analytical SEC ⋅ >95% by SDS Page |
| Product Preparation: | Functional grade preclinical antibodies are manufactured in an animal free facility using in vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. |
| Applications: | FC, In Vivo |
| Reactivity: | Mouse |
| Host Species: | Rat |
| Specificity: | Clone 480.1 activity is directed against murine CD226 (DNAM-1; PTA-1). |
| Antigen Distribution: | mCD226 is expressed on the surface of differentiated Th1 cells, CD8+ T cells, subsets of naïve CD11b+ macrophages and NK cells, and activated CD4+ cells. |
| Immunogen: | Th1 polarized T cell clones |
| Concentration: | ≥ 5.0 mg/ml |
| Endotoxin Level: | <1.0 EU/µg as determined by the LAL method |
| Formulation: | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration. |
| Purity: | ≥95% monomer by analytical SEC ⋅ >95% by SDS Page |
| Preparation: | Functional grade preclinical antibodies are manufactured in an animal free facility using in vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. |
| Storage and Handling: | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -70°C. Avoid Repeated Freeze Thaw Cycles. |
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