Anti-Mouse CD127 (IL-7Rα) [A7R34] In Vivo Antibody - Low Endotoxin
- SKU:
- IVMB0343
- Product Type:
- In Vivo Monoclonal Antibody
- Clone:
- A7R34
- Protein:
- CD127
- Isotype:
- IgG2a k
- Reactivity:
- Mouse
- Synonyms:
- IL-7R alpha
- Synonyms:
- Interleukin-7 receptor alpha
- Synonyms:
- IL-7R alpha chain
- Research Area:
- Immunology
- Endotoxin Level:
- Low Endotoxin
- Host Species:
- Rat
- Applications:
- Blocking
- Applications:
- CyTOF
- Applications:
- FA
- Applications:
- FC
- Applications:
- IF Staining
- Applications:
- IHC FF
- Applications:
- In Vivo
- Applications:
- IP
- Applications:
- WB
Description
Product Name: | Anti-Mouse CD127 (IL-7Rα) In Vivo Antibody - Low Endotoxin |
Product Code: | IVMB0343 |
Size: | 1 mg |
Clone: | A7R34 |
Protein: | CD127 |
Product Type: | Monoclonal Antibody |
Synonyms: | IL-7Rα, Interleukin-7 receptor alpha, IL-7Rα chain |
Isotype: | IgG2a k |
Reactivity: | Mouse |
Applications: | B, CyTOF®, FA, FC, IF Staining, IHC FF, In Vivo, IP, WB |
Formulation: | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration. |
Endotoxin Level: | <0.01 EU/µg as determined by the LAL method |
Purity: | >95% monomer by analytical SEC |
Product Preparation: | Functional grade preclinical antibodies are manufactured in an animal free facility using in vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. |
Applications: | B, CyTOF®, FA, FC, IF Staining, IHC FF, In Vivo, IP, WB |
Reactivity: | Mouse |
Host Species: | Rat |
Specificity: | Clone A7R34 recognizes an epitope on mouse CD127. |
Antigen Distribution: | IL-7Rα is expressed on bone marrow lymphoid precursors, pro-B cells, monocytes/macrophages, NK-cells, naïve T cells, memory CD4+ and CD8+ T cells, intestinal colorectal and renal carcinoma cell lines, and keratinocytes. |
Immunogen: | IL-7Ra-IgG1 fusion protein |
Concentration: | ≥ 5.0 mg/ml |
Endotoxin Level: | <0.01 EU/µg as determined by the LAL method |
Formulation: | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration. |
Purity: | >95% monomer by analytical SEC |
Preparation: | Functional grade preclinical antibodies are manufactured in an animal free facility using in vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. |
Storage and Handling: | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
Protein: | CD127 |
Function: | T cell and immature B cell proliferation and development |
Ligand/Receptor: | IL-7 |
Research Area: | Immunology |
Pathogen Testing: | To protect mouse colonies from infection by pathogens and to assure that experimental preclinical data is not affected by such pathogens, all of Assay Genie's Purified Functional Antibodies are tested and guaranteed to be negative for all pathogens in the IDEXX IMPACT I Mouse Profile. |
Shipping: | 2-8°C |
PubMed: | CD127 |
NCBI Gene Bank ID: | 16197 |
UniProt: | CD127 |