Anti-MonoMethyl-H2B-E105 Antibody (CAB20230)
- SKU:
- CAB20230
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- H2B.1
- Synonyms:
- H2B/f
- Synonyms:
- H2BFF
- Synonyms:
- HIST1H2BB
Description
| Product Name: | MonoMethyl-H2B-E105 Rabbit pAb |
| Product Code: | CAB20230 |
| Size: | 50uL, 100uL |
| Synonyms: | H2B.1, H2B/f, H2BFF, HIST1H2BB |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | A synthetic monomethylated peptide around E105 of human H2B. |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | HeLa, NIH/3T3 |
| Immunogen: | A synthetic monomethylated peptide around E105 of human H2B. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 3018 |
| Uniprot: | P33778 |
| Calculated MW: | 14kDa |
| Observed MW: | 15KDa |
| UniProt Protein Function: | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| NCBI Summary: | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015] |
| UniProt Code: | P33778 |
| NCBI GenInfo Identifier: | 462236 |
| NCBI Gene ID: | 3018 |
| NCBI Accession: | P33778.2 |
| UniProt Secondary Accession: | P33778,Q4KN36, |
| UniProt Related Accession: | P33778 |
| Molecular Weight: | 13,950 Da |
| NCBI Full Name: | Histone H2B type 1-B |
| NCBI Synonym Full Names: | histone cluster 1 H2B family member b |
| NCBI Official Symbol: | HIST1H2BB |
| NCBI Official Synonym Symbols: | H2B.1; H2B/f; H2BFF |
| NCBI Protein Information: | histone H2B type 1-B |
| UniProt Protein Name: | Histone H2B type 1-B |
| UniProt Synonym Protein Names: | Histone H2B.1; Histone H2B.f; H2B/f |
| Protein Family: | Histone |
| UniProt Gene Name: | HIST1H2BB |
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