Anti-MNX1/HB9/HLXB9 Antibody (CAB20537)
- SKU:
- CAB20537
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- HB9
- Synonyms:
- HLXB9
- Synonyms:
- HOXHB9
- Synonyms:
- SCRA1
Description
| Product Name: | MNX1/HB9/HLXB9 Rabbit pAb |
| Product Code: | CAB20537 |
| Size: | 50uL, 100uL |
| Synonyms: | HB9, HLXB9, HOXHB9, SCRA1 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human MNX1/HB9/HLXB9. |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, Mouse thymus, Rat liver |
| Immunogen: | Recombinant protein of human MNX1/HB9/HLXB9. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 3110 |
| Uniprot: | P50219 |
| Calculated MW: | 41kDa |
| Observed MW: | 55KDa |
| UniProt Protein Function: | MNX1: Putative transcription factor involved in pancreas development and function. Defects in MNX1 are a cause of Currarino syndrome (CURRAS). The triad of a presacral tumor, sacral agenesis and anorectal malformation constitutes the Currarino syndrome which is caused by dorsal-ventral patterning defects during embryonic development. The syndrome occurs in the majority of patients as an autosomal dominant trait. |
| UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 7q36 Cellular Component: cytoplasm; nucleolus; nucleus Molecular Function:transcription factor activity Biological Process: anatomical structure morphogenesis; endocrine pancreas development; humoral immune response; neurite morphogenesis; regulation of transcription from RNA polymerase II promoter; spinal cord motor neuron cell fate specification Disease: Currarino Syndrome |
| NCBI Summary: | This gene encodes a nuclear protein, which contains a homeobox domain and is a transcription factor. Mutations in this gene result in Currarino syndrome, an autosomic dominant congenital malformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] |
| UniProt Code: | P50219 |
| NCBI GenInfo Identifier: | 259016336 |
| NCBI Gene ID: | 3110 |
| NCBI Accession: | P50219.3 |
| UniProt Secondary Accession: | P50219,Q9Y648, F5H401, |
| UniProt Related Accession: | P50219 |
| Molecular Weight: | 20,553 Da |
| NCBI Full Name: | Motor neuron and pancreas homeobox protein 1 |
| NCBI Synonym Full Names: | motor neuron and pancreas homeobox 1 |
| NCBI Official Symbol: | MNX1 |
| NCBI Official Synonym Symbols: | HB9; HLXB9; SCRA1; HOXHB9 |
| NCBI Protein Information: | motor neuron and pancreas homeobox protein 1 |
| UniProt Protein Name: | Motor neuron and pancreas homeobox protein 1 |
| UniProt Synonym Protein Names: | Homeobox protein HB9 |
| Protein Family: | Motor neuron and pancreas homeobox protein |
| UniProt Gene Name: | MNX1 |
| UniProt Entry Name: | MNX1_HUMAN |
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