Epigenetics & Nuclear Signaling Antibodies 2
Anti-MLLT3 Antibody (CAB15690)
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- SKU:
- CAB15690
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-MLLT3 Antibody |
| Antibody SKU: | CAB15690 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human MLLT3 (NP_004520.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Jurkat, HeLa, Mouse spleen, Mouse testis, Mouse brain, Rat testis |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human MLLT3 (NP_004520.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MASS CAVQ VKLE LGHR AQVR KKPT VEGF THDW MVFV RGPE HSNI QHFV EKVV FHLH ESFP RPKR VCKD PPYK VEES GYAG FILP IEVY FKNK EEPR KVRF DYDL FLHL EGHP PVNH LRCE KLTF NNPT EDFR RKLL KAGG DPNR SIHT SS |
| Gene ID: | 4300 |
| Uniprot: | P42568 |
| Cellular Location: | Nucleus |
| Calculated MW: | 63kDa |
| Observed MW: | 80kDa |
| Synonyms: | MLLT3, AF9, YEATS3 |
| Background: |
| UniProt Protein Function: | MLLT3: A chromosomal aberration involving MLLT3 is associated with acute leukemias. Translocation t(9;11)(p22;q23) with MLL/HRX. The result is a rogue activator protein. |
| UniProt Protein Details: | Protein type:Cell development/differentiation; Oncoprotein Chromosomal Location of Human Ortholog: 9p22 Cellular Component: transcription elongation factor complex; nucleus Molecular Function:protein binding Biological Process: anterior/posterior pattern formation; segment specification; regulation of transcription, DNA-dependent; transcription, DNA-dependent |
| UniProt Code: | P42568 |
| NCBI GenInfo Identifier: | 215273971 |
| NCBI Gene ID: | 4300 |
| NCBI Accession: | P42568.2 |
| UniProt Secondary Accession: | P42568,Q8IVB0, B1AMQ2, B2R7B3, B7Z755, D3DRJ8, |
| UniProt Related Accession: | P42568 |
| Molecular Weight: | 568 |
| NCBI Full Name: | Protein AF-9 |
| NCBI Synonym Full Names: | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 |
| NCBI Official Symbol: | MLLT3 |
| NCBI Official Synonym Symbols: | AF9; YEATS3 |
| NCBI Protein Information: | protein AF-9; YEATS domain-containing protein 3; ALL1-fused gene from chromosome 9 protein; myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); translocated to, 3 |
| UniProt Protein Name: | Protein AF-9 |
| UniProt Synonym Protein Names: | ALL1-fused gene from chromosome 9 protein; Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein; YEATS domain-containing protein 3 |
| UniProt Gene Name: | MLLT3 |
| UniProt Entry Name: | AF9_HUMAN |
 | Western blot analysis of extracts of various cell lines, using MLLT3 antibody (CAB15690) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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