Description
Product Name: | MLLT11 Rabbit pAb |
Product Code: | CAB20410 |
Size: | 50uL, 100uL |
Synonyms: | AF1Q |
Applications: | WB |
Reactivity: | Human |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human MLLT11 (NP_006809.1). |
Applications: | WB |
Recommended Dilutions: | WB 1:500 - 1:2000 |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human MLLT11 (NP_006809.1). |
Purification Method: | Affinity purification |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 10962 |
Uniprot: | Q13015 |
Calculated MW: | 10kDa |
Observed MW: | Refer to figures |
UniProt Protein Function: | |
UniProt Protein Details: | |
NCBI Summary: | The gene variously symbolized ALL1, HRX, or MLL located on 11q23 has been demonstrated to be fused with a number of translocation partners in cases of leukemia. t(1;11)(q21;q23) translocations that fused the MLL gene to a gene on chromosomal band 1q21 in 2 infants with acute myelomonocytic leukemia have been demonstrated. The N-terminal portion of the MLL gene is critical for leukemogenesis in translocations involving band 11q23. This gene encodes 90 amino acids. It was found to be highly expressed in the thymus but not in peripheral lymphoid tissues. In contrast to its restricted distribution in normal hematopoietic tissue, this gene was expressed in all leukemic cell lines tested. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q13015 |
NCBI GenInfo Identifier: | 16307091 |
NCBI Gene ID: | 10962 |
NCBI Accession: | BC009624 |
UniProt Secondary Accession: | Q13015 |
UniProt Related Accession: | Q13015 |
Molecular Weight: | |
NCBI Full Name: | Homo sapiens myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11, mRNA |
NCBI Synonym Full Names: | MLLT11 transcription factor 7 cofactor |
NCBI Official Symbol: | MLLT11 |
NCBI Official Synonym Symbols: | AF1Q |
NCBI Protein Information: | protein AF1q |
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Protein Family: | |
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