Anti-MLH1 Antibody (CAB20544)
- SKU:
- CAB20544
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- COCA2
- Synonyms:
- FCC2
- Synonyms:
- HNPCC
- Synonyms:
- HNPCC2
- Synonyms:
- hMLH1
Description
| Product Name: | MLH1 Mouse mAb |
| Product Code: | CAB20544 |
| Size: | 50uL, 100uL |
| Synonyms: | COCA2, FCC2, HNPCC, HNPCC2, hMLH1 |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human MLH1. |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human |
| Immunogen: | Recombinant protein of human MLH1. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 4292 |
| Cellular Location: | Nucleus |
| Observed MW: | Refer to figures |
| Background: | This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.[provided by RefSeq, Nov 2009] |
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