Cell Biology Antibodies 10

Anti-MLANA Antibody (CAB6290)

(No reviews yet) Write a Review
SKU:
CAB6290
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-MLANA Antibody
Antibody SKU:CAB6290
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 48-118 of human MLANA (NP_005502.1).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:M21, Mouse eye, Rat eye
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 48-118 of human MLANA (NP_005502.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:CRRR NGYR ALMD KSLH VGTQ CALT RRCP QEGF DHRD SKVS LQEK NCEP VVPN APPA YEKL SAEQ SPPP YSP
Gene ID:2315
Uniprot:Q16655
Cellular Location:Endoplasmic reticulum membrane, Golgi apparatus, Melanosome, Single-pass type III membrane protein, trans-Golgi network membrane
Calculated MW:13kDa
Observed MW:18kDa
Synonyms:MLANA, MART-1, MART1, melan-A
Background:
UniProt Protein Function:MLANA: Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.
UniProt Protein Details:

Protein type:Membrane protein, integral; Cell surface

Chromosomal Location of Human Ortholog: 9p24.1

Cellular Component: endoplasmic reticulum membrane; Golgi apparatus; integral to plasma membrane; melanosome; trans-Golgi network

Molecular Function:protein binding

UniProt Code:Q16655
NCBI GenInfo Identifier:2833278
NCBI Gene ID:2315
NCBI Accession:Q16655.1
UniProt Secondary Accession:Q16655,Q6ICU4,
UniProt Related Accession:Q16655
Molecular Weight:13,157 Da
NCBI Full Name:Melanoma antigen recognized by T-cells 1
NCBI Synonym Full Names:melan-A
NCBI Official Symbol:MLANA  
NCBI Official Synonym Symbols:MART1; MART-1  
NCBI Protein Information:melanoma antigen recognized by T-cells 1
UniProt Protein Name:Melanoma antigen recognized by T-cells 1
UniProt Synonym Protein Names:Antigen LB39-AA; Antigen SK29-AA; Protein Melan-A
Protein Family:Melanoma antigen recognized by T-cells
UniProt Gene Name:MLANA  
UniProt Entry Name:MAR1_HUMAN
Anti-MLANA Antibody (CAB6290)Western blot analysis of extracts of M21 cells, using MLANA antibody (CAB6290) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Basic Kit (RM00020)._Exposure time: 90s.
Anti-MLANA Antibody (CAB6290)Western blot analysis of extracts of various cell lines, using MLANA antibody (CAB6290) at 1:3000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 60s.
Anti-MLANA Antibody (CAB6290)Immunofluorescence analysis of U2OS cells using MLANA antibody (CAB6290). Blue: DAPI for nuclear staining.
View AllClose

0 Reviews

View AllClose

Related Products