Cell Biology Antibodies 3
Anti-MIPEP Antibody (CAB12640)
- SKU:
- CAB12640
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Antibody Name: | Anti-MIPEP Antibody |
Antibody SKU: | CAB12640 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Human |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 504-713 of human MIPEP (NP_005923.2). |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Human |
Positive Samples: | HT-29 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 504-713 of human MIPEP (NP_005923.2). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | MLGR TRYQ HVTG TRCP TDFA EVPS ILME YFAN DYRV VNQF ARHY QTGQ PLPK NMVS RLCE SKKV CAAA DMQL QVFY ATLD QIYH GKHP LRNS TTDI LKET QEKF YGLP YVPN TAWQ LRFS HLVG YGAR YYSY LMSR AVAS MVWK ECFL QDPF NRAA GERY RREM LAHG GGRE PMLM VEGM LQKC PSVD DFVS ALVS DLDL DFET FLMD SE |
Gene ID: | 4285 |
Uniprot: | Q99797 |
Cellular Location: | Mitochondrion matrix |
Calculated MW: | 80kDa |
Observed MW: | 81kDa |
Synonyms: | MIPEP, COXPD31, HMIP, MIP |
Background: | The product of this gene performs the final step in processing a specific class of nuclear-encoded proteins targeted to the mitochondrial matrix or inner membrane. This protein is primarily involved in the maturation of oxidative phosphorylation (OXPHOS)-related proteins. This gene may contribute to the functional effects of frataxin deficiency and the clinical manifestations of Friedreich ataxia. |
UniProt Protein Function: | MIPEP: Cleaves proteins, imported into the mitochondrion, to their mature size. Belongs to the peptidase M3 family. |
UniProt Protein Details: | Protein type:Mitochondrial; EC 3.4.24.59; Protease Chromosomal Location of Human Ortholog: 13q12 Cellular Component: mitochondrion Biological Process: mitochondrial protein processing; peptide metabolic process |
NCBI Summary: | The product of this gene performs the final step in processing a specific class of nuclear-encoded proteins targeted to the mitochondrial matrix or inner membrane. This protein is primarily involved in the maturation of oxidative phosphorylation (OXPHOS)-related proteins. This gene may contribute to the functional effects of frataxin deficiency and the clinical manifestations of Friedreich ataxia. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q99797 |
NCBI GenInfo Identifier: | 182639267 |
NCBI Gene ID: | 4285 |
NCBI Accession: | Q99797.2 |
UniProt Secondary Accession: | Q99797,Q5JV15, Q5T9Q9, Q96G65, |
UniProt Related Accession: | Q99797 |
Molecular Weight: | 80,641 Da |
NCBI Full Name: | Mitochondrial intermediate peptidase |
NCBI Synonym Full Names: | mitochondrial intermediate peptidase |
NCBI Official Symbol: | MIPEP |
NCBI Official Synonym Symbols: | MIP; HMIP |
NCBI Protein Information: | mitochondrial intermediate peptidase |
UniProt Protein Name: | Mitochondrial intermediate peptidase |
Protein Family: | Mitochondrial intermediate peptidase |
UniProt Gene Name: | MIPEP |
UniProt Entry Name: | MIPEP_HUMAN |
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