Cell Biology Antibodies 17
Anti-MIER1 Antibody (CAB18480)
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- SKU:
- CAB18480
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-MIER1 Antibody |
| Antibody SKU: | CAB18480 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human MIER1. |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: | HeLa, A-549, Mouse brain |
| Immunogen: | Recombinant protein of human MIER1. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 57708 |
| Uniprot: | Q8N108 |
| Cellular Location: | |
| Calculated MW: | 9kDa/42-63kDa |
| Observed MW: | 58kDa |
 | Western blot - MIER1 Rabbit pAb (CAB18480) |
| Synonyms: | ER1, MI-ER1, MIER1 |
| Background: | This gene encodes a protein that was first identified in Xenopus laevis by its role in a mesoderm induction early response (MIER). The encoded protein functions as a transcriptional regulator. Alternatively spliced transcript variants encode multiple isoforms, some of which lack a C-terminal nuclear localization signal. |
| UniProt Protein Function: | MIER1: a transcriptional repressor which acts through recruitment of HDAC1. Contains a Myb-like DNA-binding and ELM2 domain. Its expression is associated with breast carcinoma |
| UniProt Protein Details: | Protein type:Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 1p31.3 Cellular Component: nucleoplasm; transcriptional repressor complex Molecular Function:protein binding; signal transducer activity Biological Process: positive regulation of chromatin silencing; positive regulation of I-kappaB kinase/NF-kappaB cascade |
| NCBI Summary: | This gene encodes a protein that was first identified in Xenopus laevis by its role in a mesoderm induction early response (MIER). The encoded protein functions as a transcriptional regulator. Alternatively spliced transcript variants encode multiple isoforms, some of which lack a C-terminal nuclear localization signal. [provided by RefSeq, May 2013] |
| UniProt Code: | Q8N108 |
| NCBI GenInfo Identifier: | 380865399 |
| NCBI Gene ID: | 57708 |
| NCBI Accession: | Q8N108.2 |
| UniProt Secondary Accession: | Q8N108,Q08AE0, Q32NC4, Q5T104, Q5TAD1, Q5TAD2, Q5TAD4 Q5TAD5, Q6AHY8, Q86TB4, Q8N156, C9JFD4, |
| UniProt Related Accession: | Q8N108 |
| Molecular Weight: | 9,357 Da |
| NCBI Full Name: | Mesoderm induction early response protein 1 |
| NCBI Synonym Full Names: | MIER1 transcriptional regulator |
| NCBI Official Symbol: | MIER1 |
| NCBI Official Synonym Symbols: | ER1; MI-ER1 |
| NCBI Protein Information: | mesoderm induction early response protein 1 |
| UniProt Protein Name: | Mesoderm induction early response protein 1 |
| Protein Family: | Mesoderm induction early response protein |
| UniProt Gene Name: | MIER1 |
| UniProt Entry Name: | MIER1_HUMAN |
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