Cell Biology Antibodies 3
Anti-MGAT4C Antibody (CAB14326)
- SKU:
- CAB14326
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Antibody Name: | Anti-MGAT4C Antibody |
Antibody SKU: | CAB14326 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Human |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 299-478 of human MGAT4C (NP_037376.2). |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Human |
Positive Samples: | U-87MG |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 299-478 of human MGAT4C (NP_037376.2). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | KNVI RFKP SLFQ HMGY YSSY KGTE NKLK DDDF EEES FDIP DNPP ASLY TNMN VFEN YEAS KAYS SVDE YFWG KPPS TGDV FVIV FENP IIIK KIKV NTGT EDRQ NDIL HHGA LDVG ENVM PSKQ RRQC STYL RLGE FKNG NFEM SGVN QKIP FDIH CMRI YVTK TQKE WLII RSIS IWTS |
Gene ID: | 25834 |
Uniprot: | Q9UBM8 |
Cellular Location: | Golgi apparatus membrane, Single-pass type II membrane protein |
Calculated MW: | 56kDa/59kDa |
Observed MW: | 56kDa |
Synonyms: | MGAT4C, GNTIVH, HGNT-IV-H |
Background: |
UniProt Protein Function: | MGAT4C: Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N- linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Does not catalyze the transfer of GlcNAc to the Manalpha1-6 arm to form GlcNAcBeta1-4Manalpha1-6 linkage ('GnT-VI' activity). Belongs to the glycosyltransferase 54 family. |
UniProt Protein Details: | Protein type:Membrane protein, integral; EC 2.4.1.145; Transferase Chromosomal Location of Human Ortholog: 12q21 Cellular Component: Golgi membrane Molecular Function:alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity Biological Process: N-glycan processing |
UniProt Code: | Q9UBM8 |
NCBI GenInfo Identifier: | 296437368 |
NCBI Gene ID: | 25834 |
NCBI Accession: | Q9UBM8.2 |
UniProt Secondary Accession: | Q9UBM8,Q4G199, Q9UIU5, B4DRH2, |
UniProt Related Accession: | Q9UBM8 |
Molecular Weight: | 59,465 Da |
NCBI Full Name: | Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C |
NCBI Synonym Full Names: | MGAT4 family member C |
NCBI Official Symbol: | MGAT4C |
NCBI Official Synonym Symbols: | GNTIVH; HGNT-IV-H |
NCBI Protein Information: | alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C |
UniProt Protein Name: | Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C |
UniProt Synonym Protein Names: | N-acetylglucosaminyltransferase IV homolog; hGnT-IV-H; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc; GlcNAc-T IVc; GnT-IVc; N-acetylglucosaminyltransferase IVc; UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc |
Protein Family: | Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase |
UniProt Gene Name: | MGAT4C |
UniProt Entry Name: | MGT4C_HUMAN |
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