Cell Biology Antibodies 13

Anti-MGAM Antibody (CAB17584)

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SKU:
CAB17584
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-MGAM Antibody
Antibody SKU:CAB17584
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 860-1090 of human MGAM (NP_004659.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:293T, K-562
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 860-1090 of human MGAM (NP_004659.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:ETKD TVAN KVYL LCEF SVTQ NRLE VNIS QSTY KDPN NLAF NEIK ILGT EEPS NVTV KHNG VPSQ TSPT VTYD SNLK VAII TDID LLLG EAYT VEWS IKIR DEEK IDCY PDEN GASA ENCT ARGC IWEA SNSS GVPF CYFV NDLY SVSD VQYN SHGA TADI SLKS SVYA NAFP STPV NPLR LDVT YHKN EMLQ FKIY DPNK NRYE VPVP LNIP SMPS STPE GQLY DVLI KKN
Gene ID:8972
Uniprot:O43451
Cellular Location:
Calculated MW:
Observed MW:190kDa
Anti-MGAM Antibody (CAB17584)Western blot - MGAM Polyclonal Antibody (CAB17584)
Synonyms:MG, MGA, MGAM
Background:This gene encodes maltase-glucoamylase, which is a brush border membrane enzyme that plays a role in the final steps of digestion of starch. The protein has two catalytic sites identical to those of sucrase-isomaltase, but the proteins are only 59% homologous. Both are members of glycosyl hydrolase family 31, which has a variety of substrate specificities. [provided by RefSeq, Jul 2008]
UniProt Protein Function:MGAM: May serve as an alternate pathway for starch digestion when luminal alpha-amylase activity is reduced because of immaturity or malnutrition. May play a unique role in the digestion of malted dietary oligosaccharides used in food manufacturing. Belongs to the glycosyl hydrolase 31 family.
UniProt Protein Details:

Protein type:Carbohydrate Metabolism - galactose; Carbohydrate Metabolism - starch and sucrose; EC 3.2.1.20; EC 3.2.1.3; Hydrolase; Membrane protein, integral

Chromosomal Location of Human Ortholog: 7q34

Cellular Component: apical plasma membrane; integral component of membrane; plasma membrane

Molecular Function:alpha-1,4-glucosidase activity; amylase activity; carbohydrate binding; catalytic activity; glucan 1,4-alpha-glucosidase activity; maltase activity

Biological Process: maltose metabolic process; neutrophil degranulation; polysaccharide digestion; starch catabolic process

NCBI Summary:This gene encodes maltase-glucoamylase, which is a brush border membrane enzyme that plays a role in the final steps of digestion of starch. The protein has two catalytic sites identical to those of sucrase-isomaltase, but the proteins are only 59% homologous. Both are members of glycosyl hydrolase family 31, which has a variety of substrate specificities. [provided by RefSeq, Jul 2008]
UniProt Code:O43451
NCBI GenInfo Identifier:221316699
NCBI Gene ID:8972
NCBI Accession:NP_004659.2
UniProt Secondary Accession:O43451,Q0VAX6, Q75ME7, Q86UM5,
UniProt Related Accession:O43451
Molecular Weight:209,852 Da
NCBI Full Name:maltase-glucoamylase, intestinal
NCBI Synonym Full Names:maltase-glucoamylase
NCBI Official Symbol:MGAM  
NCBI Official Synonym Symbols:MG; MGA  
NCBI Protein Information:maltase-glucoamylase, intestinal
UniProt Protein Name:Maltase-glucoamylase, intestinal
UniProt Synonym Protein Names:Maltase (EC:3.2.1.20)Alternative name(s):Alpha-glucosidase
Protein Family:MAX gene-associated protein
UniProt Gene Name:MGAM  
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