Cell Biology Antibodies 9
Anti-MFF Antibody (CAB4874)
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- SKU:
- CAB4874
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- MFF
- Synonyms:
- C2orf33
- Synonyms:
- EMPF2
- Synonyms:
- GL004
- Research Area:
- Cell Biology
Description
| Product Name: | MFF Rabbit pAb |
| Product Code: | CAB4874 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | MFF, C2orf33, EMPF2, GL004 |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 15-170 of human MFF (NP_064579.3). |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human |
| Positive Samples: | HeLa |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 15-170 of human MFF (NP_064579.3). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | SRAA FPSP TAAE MAEI SRIQ YEME YTEG ISQR MRVP EKLK VAPP NADL EQGF QEGV PNAS VIMQ VPER IVVA GNNE DVSF SRPA DLDL IQST PFKP LALK TPPR VLTL SERP LDFL DLER PPTT PQNE EIRA VGRL KRER SMSE NAVR QNGQ LVRN |
| Gene ID: | 56947 |
| Uniprot: | Q9GZY8 |
| Cellular Location: | Cytoplasmic vesicle, Mitochondrion outer membrane, Peroxisome, Single-pass type IV membrane protein, secretory vesicle, synaptic vesicle |
| Calculated MW: | 25kDa/27kDa/32kDa/38kDa |
| Observed MW: | 38kDa |
| UniProt Protein Function: | MFF: Plays a role in mitochondrial and peroxisomal fission. Belongs to the tango11 family. 5 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Mitochondrial Chromosomal Location of Human Ortholog: 2q36.3 Cellular Component: mitochondrial outer membrane; mitochondrion; peroxisome Molecular Function:protein binding; protein homodimerization activity Biological Process: mitochondrial fission; mitochondrial fragmentation during apoptosis; mitochondrial fusion; peroxisome fission; protein homooligomerization; protein targeting to mitochondrion; release of cytochrome c from mitochondria |
| NCBI Summary: | This is a nuclear gene encoding a protein that functions in mitochondrial and peroxisomal fission. The encoded protein recruits dynamin-1-like protein (DNM1L) to mitochondria. There are multiple pseudogenes for this gene on chromosomes 1, 5, and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013] |
| UniProt Code: | Q9GZY8 |
| NCBI GenInfo Identifier: | 74725008 |
| NCBI Gene ID: | 56947 |
| NCBI Accession: | Q9GZY8.1 |
| UniProt Secondary Accession: | Q9GZY8,Q567U1, Q658R6, Q9BVZ1, Q9H690, Q9NRG8, |
| UniProt Related Accession: | Q9GZY8 |
| Molecular Weight: | 38kDa |
| NCBI Full Name: | Mitochondrial fission factor |
| NCBI Synonym Full Names: | mitochondrial fission factor |
| NCBI Official Symbol: | MFF |
| NCBI Official Synonym Symbols: | EMPF2; GL004; C2orf33 |
| NCBI Protein Information: | mitochondrial fission factor |
| UniProt Protein Name: | Mitochondrial fission factor |
| Protein Family: | Mitochondrial fission factor |
| UniProt Gene Name: | MFF |
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