Cell Biology Antibodies 1

Anti-MFAP2 Antibody (CAB10230)

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SKU:
CAB10230
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-MFAP2 Antibody
Antibody SKU:CAB10230
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 18-183 of human MFAP2 (NP_059453.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:HeLa, OVCAR3, MCF7, Mouse lung, Mouse brain, Rat lung
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 18-183 of human MFAP2 (NP_059453.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:QGQY DLDP LPPF PDHV QYTH YSDQ IDNP DYYD YQEV TPRP SEEQ FQFQ SQQQ VQQE VIPA PTPE PGNA ELEP TEPG PLDC REEQ YPCT RLYS IHRP CKQC LNEV CFYS LRRV YVIN KEIC VRTV CAHE ELLR ADLC RDKF SKCG VMAS SGLC QSVA ASCA RSCG SC
Gene ID:4237
Uniprot:P55001
Cellular Location:Secreted, extracellular matrix, extracellular space
Calculated MW:17kDa/20kDa
Observed MW:31kDa
Synonyms:MFAP2, MAGP, MAGP-1, MAGP1
Background:Microfibrillar-associated protein 2 is a major antigen of elastin-associated microfibrils and a candidate for involvement in the etiology of inherited connective tissue diseases. Four transcript variants encoding two different isoforms have been found for this gene.
UniProt Protein Function:MFAP2: Component of the elastin-associated microfibrils. Belongs to the MFAP family. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 1p36.1-p35

Cellular Component: extracellular region; microfibril

Biological Process: embryonic eye morphogenesis; extracellular matrix organization and biogenesis; post-embryonic eye morphogenesis

NCBI Summary:Microfibrillar-associated protein 2 is a major antigen of elastin-associated microfibrils and a candidate for involvement in the etiology of inherited connective tissue diseases. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
UniProt Code:P55001
NCBI GenInfo Identifier:1708914
NCBI Gene ID:4237
NCBI Accession:P55001.1
UniProt Secondary Accession:P55001,Q53X60, Q5JXY0,
UniProt Related Accession:P55001
Molecular Weight:17,444 Da
NCBI Full Name:Microfibrillar-associated protein 2
NCBI Synonym Full Names:microfibrillar associated protein 2
NCBI Official Symbol:MFAP2  
NCBI Official Synonym Symbols:MAGP; MAGP1; MAGP-1  
NCBI Protein Information:microfibrillar-associated protein 2
UniProt Protein Name:Microfibrillar-associated protein 2
UniProt Synonym Protein Names:Microfibril-associated glycoprotein 1; MAGP; MAGP-1
Protein Family:Microfibrillar-associated protein
UniProt Gene Name:MFAP2  
UniProt Entry Name:MFAP2_HUMAN
Anti-MFAP2 Antibody (CAB10230)Western blot analysis of extracts of various cell lines, using MFAP2 antibody (CAB10230) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
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