Anti-Methyl-RPL3-H245 Antibody (CAB18821)

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SKU:
CAB18821
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
RPL3
Synonyms:
ASC-1
Synonyms:
L3
Synonyms:
TARBP-B
Synonyms:
ribosomal protein L3
Research Area:
Cell Biology

Description

Product Name:Methyl-RPL3-H245 Rabbit pAb
Product Code:CAB18821
Size:20uL, 50uL, 100uL
Synonyms:RPL3, ASC-1, L3, TARBP-B, ribosomal protein L3
Applications:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:A synthetic peptide of human Methyl-RPL3-H245, 3-methyl (tau-methyl).
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human
Immunogen:A synthetic peptide of human Methyl-RPL3-H245, 3-methyl (tau-methyl).
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:6122
Uniprot:P39023
Cellular Location:Cytoplasm, Nucleus, nucleolus
Calculated MW:46kDa
Observed MW:Refer to figures
UniProt Protein Function:RPL3: The L3 protein is a component of the large subunit of cytoplasmic ribosomes. Belongs to the ribosomal protein L3P family.
UniProt Protein Details:

Protein type:Translation; Nucleolus; Ribosomal

Chromosomal Location of Human Ortholog: 22q13

Cellular Component: nucleoplasm; focal adhesion; cytoplasm; nucleolus; nucleus; cytosol

Molecular Function:structural constituent of ribosome; RNA binding

Biological Process: SRP-dependent cotranslational protein targeting to membrane; translational elongation; cellular protein metabolic process; viral reproduction; translation; translational initiation; mRNA catabolic process, nonsense-mediated decay; gene expression; viral transcription; viral infectious cycle; translational termination

NCBI Summary:Ribosomes, the complexes that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L3P family of ribosomal proteins and it is located in the cytoplasm. The protein can bind to the HIV-1 TAR mRNA, and it has been suggested that the protein contributes to tat-mediated transactivation. This gene is co-transcribed with several small nucleolar RNA genes, which are located in several of this gene's introns. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
UniProt Code:P39023
NCBI GenInfo Identifier:730565
NCBI Gene ID:6122
NCBI Accession:P39023.2
UniProt Secondary Accession:P39023,Q15548, Q5I0G0, B2RDV9,
UniProt Related Accession:P39023
Molecular Weight:403
NCBI Full Name:60S ribosomal protein L3
NCBI Synonym Full Names:ribosomal protein L3
NCBI Official Symbol:RPL3  
NCBI Official Synonym Symbols:L3; ASC-1; TARBP-B  
NCBI Protein Information:60S ribosomal protein L3; hypothetical protein; HIV-1 TAR RNA-binding protein B; ribosomal protein L3, isoform a
UniProt Protein Name:60S ribosomal protein L3
UniProt Synonym Protein Names:HIV-1 TAR RNA-binding protein B; TARBP-B
Protein Family:Ribosomal protein
UniProt Gene Name:RPL3  
UniProt Entry Name:RL3_HUMAN
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