Epigenetics & Nuclear Signaling Antibodies 2
Anti-MED28 Antibody (CAB15517)
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- SKU:
- CAB15517
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-MED28 Antibody |
| Antibody SKU: | CAB15517 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-178 of human MED28 (NP_079481.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:200 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-178 of human MED28 (NP_079481.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MAAP LGGM FSGQ PPGP PQAP PGLP GQAS LLQA APGA PRPS SSTL VDEL ESSF EACF ASLV SQDY VNGT DQEE IRTG VDQC IQKF LDIA RQTE CFFL QKRL QLSV QKPE QVIK EDVS ELRN ELQR KDAL VQKH LTKL RHWQ QVLE DINV QHKK PADI PQGS LAYL EQAS ANIP APLK PT |
| Gene ID: | 80306 |
| Uniprot: | Q9H204 |
| Cellular Location: | Cytoplasm, Membrane, Nucleus, Peripheral membrane protein |
| Calculated MW: | 19kDa |
| Observed MW: | Refer to figures |
| Synonyms: | MED28, 1500003D12Rik, EG1, magicin |
| Background: |
| UniProt Protein Function: | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May be part of a complex containing NF2/merlin that participates in cellular signaling to the actin cytoskeleton downstream of tyrosine kinase signaling pathways. |
| UniProt Code: | Q9H204 |
| NCBI GenInfo Identifier: | 52851391 |
| NCBI Gene ID: | 80306 |
| NCBI Accession: | NP_079481.2 |
| UniProt Secondary Accession: | Q9H204,Q9BZJ5, |
| UniProt Related Accession: | Q9H204 |
| Molecular Weight: | 19 |
| NCBI Full Name: | mediator of RNA polymerase II transcription subunit 28 |
| NCBI Synonym Full Names: | mediator complex subunit 28 |
| NCBI Official Symbol: | MED28 |
| NCBI Official Synonym Symbols: | EG1; magicin; 1500003D12Rik |
| NCBI Protein Information: | mediator of RNA polymerase II transcription subunit 28 |
| UniProt Protein Name: | Mediator of RNA polymerase II transcription subunit 28 |
| UniProt Synonym Protein Names: | Endothelial-derived protein 1; Mediator complex subunit 28; Merlin and Grb2-interacting cytoskeletal protein; Magicin; Tumor angiogenesis marker EG-1 |
| Protein Family: | Mediator of RNA polymerase II transcription |
| UniProt Gene Name: | MED28 |
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