Cell Biology Antibodies 14

Anti-MED23 Antibody (CAB14090)

(No reviews yet) Write a Review
SKU:
CAB14090
Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-MED23 Antibody
Antibody SKU:CAB14090
Antibody Size:20uL, 50 uL
Application:WB
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1046-1376 of mouse MED23 (NP_001159888.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse, Rat
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1046-1376 of mouse MED23 (NP_001159888.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:NRPQ GWCL SDTY LKHA MNAR EDNP WVPE DSYY CKLI GRLV DTMA GKSP GPFP NCDW RFNE FPNP AAHA LHVT CVEL MALA VPGK DVGN ALLN VVLK SQPL VPRE NITA WMNA IGLI ITAL PEPY WIVL HDRI VNVI SSSS LTSE TEWV GYPF RLFD FTAC HQSY SEMS CSYT LALA HAVW HHSS IGQL SLIP KFLT EALL PVVK TEFQ LLYV YHLV GPFL QRFQ QERT RCMI EIGV AFYD MLLN VDQC STHL NYMD PICD FLYH MKYM FTGD SVKE QVEK IICN LKPA LKLR LRFI THIS KMEP AVPP QALN SGSP APQS NQVP ASLP VTQ
Gene ID:70208
Uniprot:
Cellular Location:Nucleus
Calculated MW:54kDa/100kDa/155kDa/156kDa
Observed MW:Refer to figures
Synonyms:MED23, ARC130, CRSP130, CRSP133, CRSP3, DRIP130, MRT18, SUR-2, SUR2
Background:The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein also acts as a metastasis suppressor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
View AllClose

0 Reviews

View AllClose

Related Products