Epigenetics & Nuclear Signaling Antibodies 1
Anti-MAZ Antibody (CAB12921)
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- SKU:
- CAB12921
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-MAZ Antibody |
| Antibody SKU: | CAB12921 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 270-420 of human MAZ (NP_001036004.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:1000 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | U-87MG |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 270-420 of human MAZ (NP_001036004.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | ASGK RIRK NHAC EMCG KAFR DVYH LNRH KLSH SDEK PYQC PVCQ QRFK RKDR MSYH VRSH DGAV HKPY NCSH CGKS FSRP DHLN SHVR QVHS TERP FKCE KCEA AFAT KDRL RAHT VRHE EKVP CHVC GKML SSAY ISDH MKVH SQGP HHV |
| Gene ID: | 4150 |
| Uniprot: | P56270 |
| Cellular Location: | Nucleus |
| Calculated MW: | 17kDa/46kDa/48kDa/51kDa |
| Observed MW: | 60kDa |
| Synonyms: | MAZ, PUR1, Pur-1, SAF-1, SAF-2, SAF-3, ZF87, ZNF801, Zif87 |
| Background: |
| UniProt Protein Function: | MAZ: a myc-associated zinc finger protein. An inflammation-responsive transcription factor with dual roles in transcription initiation and termination. Binds to two sites within the c-myc promoter. Also binds to multiple G/C-rich sites within the promoter of the SP1 family of transcription factors. Expressed in heart, brain, placenta, lung, liver, skeletal muscle and pancreas. |
| UniProt Protein Details: | Protein type:C2H2-type zinc finger protein; RNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 16p11.2 Molecular Function:protein binding Biological Process: termination of RNA polymerase II transcription; transcription initiation from RNA polymerase II promoter |
| UniProt Code: | P56270 |
| NCBI GenInfo Identifier: | 3024110 |
| NCBI Gene ID: | 4150 |
| NCBI Accession: | P56270.1 |
| UniProt Secondary Accession: | P56270,Q15703, Q8NFN7, Q99443, A8QJL9, C6G496, G5E927 H3BQD6, |
| UniProt Related Accession: | P56270 |
| Molecular Weight: | 17,763 Da |
| NCBI Full Name: | Myc-associated zinc finger protein |
| NCBI Synonym Full Names: | MYC associated zinc finger protein |
| NCBI Official Symbol: | MAZ |
| NCBI Official Synonym Symbols: | PUR1; ZF87; Pur-1; SAF-1; SAF-2; SAF-3; Zif87; ZNF801 |
| NCBI Protein Information: | myc-associated zinc finger protein |
| UniProt Protein Name: | Myc-associated zinc finger protein |
| UniProt Synonym Protein Names: | Pur-1; Purine-binding transcription factor; Serum amyloid A-activating factor-1; SAF-1; Transcription factor Zif87; ZF87; Zinc finger protein 801 |
| Protein Family: | Myc-associated zinc finger protein |
| UniProt Gene Name: | MAZ |
| UniProt Entry Name: | MAZ_HUMAN |
 | Western blot analysis of extracts of U-87MG cells, using MAZ antibody (CAB12921) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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