Cell Biology Antibodies 12
Anti-MARVELD2 Antibody (CAB8909)
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- SKU:
- CAB8909
- Product Type:
- Antibody
- Applications:
- WB
- Applications:
- IHC
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-MARVELD2 Antibody |
| Antibody SKU: | CAB8909 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human MARVELD2 (NP_001033692.2). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | SH-SY5Y |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human MARVELD2 (NP_001033692.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | ELLL GAGV FACV TAYI HKDS EWYN LFGY SQPY GMGG VGGL GSMY GGYY YTGP KTPF VLVV AGLA WITT IIIL VLGM SMYY RTIL LDSN WWPL TEFG INVA L |
| Gene ID: | 153562 |
| Uniprot: | Q8N4S9 |
| Cellular Location: | Cell junction, Cell membrane, Multi-pass membrane protein, tight junction |
| Calculated MW: | 51kDa/62kDa/64kDa |
| Observed MW: | 64kDa |
| Synonyms: | MARVELD2, DFNB49, MARVD2, MRVLDC2, Tric |
| Background: | The protein encoded by this gene is a membrane protein found at the tight junctions between epithelial cells. The encoded protein helps establish epithelial barriers such as those in the organ of Corti, where these barriers are required for normal hearing. Defects in this gene are a cause of deafness autosomal recessive type 49 (DFNB49). Two transcript variants encoding different isoforms have been found for this gene. |
| UniProt Code: | Q8N4S9 |
| NCBI GenInfo Identifier: | 289666784 |
| NCBI Gene ID: | 153562 |
| NCBI Accession: | NP_001033692.2 |
| UniProt Secondary Accession: | Q8N4S9,Q96NM9, A1BQX0, A1BQX1, A8KA97, |
| UniProt Related Accession: | Q8N4S9 |
| Molecular Weight: | 64,168 Da |
| NCBI Full Name: | MARVEL domain-containing protein 2 isoform 1 |
| NCBI Synonym Full Names: | MARVEL domain containing 2 |
| NCBI Official Symbol: | MARVELD2 |
| NCBI Official Synonym Symbols: | Tric; DFNB49; MARVD2; MRVLDC2 |
| NCBI Protein Information: | MARVEL domain-containing protein 2; tricellulin; MARVEL (membrane-associating) domain containing 2 |
| UniProt Protein Name: | MARVEL domain-containing protein 2 |
| UniProt Synonym Protein Names: | Tricellulin |
| UniProt Gene Name: | MARVELD2 |
| UniProt Entry Name: | MALD2_HUMAN |
 | Western blot analysis of extracts of SH-SY5Y cells, using MARVELD2 antibody (CAB8909) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded mouse stomach using MARVELD2 antibody (CAB8909) (40x lens). |
 | Immunohistochemistry of paraffin-embedded rat kidney using MARVELD2 antibody (CAB8909) (40x lens). |
 | Immunohistochemistry of paraffin-embedded human liver damage using MARVELD2 antibody (CAB8909) (40x lens). |
 | Immunohistochemistry of paraffin-embedded human stomach using MARVELD2 antibody (CAB8909) (40x lens). |
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