Cell Biology Antibodies 3

Anti-MARVELD2 Antibody (CAB12612)

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SKU:
CAB12612
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-MARVELD2 Antibody
Antibody SKU:CAB12612
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-195 of human MARVELD2 (NP_001033692.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:HT-29, A-549, Mouse kidney
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-195 of human MARVELD2 (NP_001033692.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MSND GRSR NRDR RYDE VPSD LPYQ DTTI RTHP TLHD SERA VSAD PLPP PPLP LQPP FGPD FYSS DTEE PAIA PDLK PVRR FVPD SWKN FFRG KKKD PEWD KPVS DIRY ISDG VECS PPAS PARP NHRS PLNS CKDP YGGS EGTF SSRK EADA VFPR DPYG SLDR HTQT VRTY SEKV EEYN LRYS YMKS WAGL LRI
Gene ID:153562
Uniprot:Q8N4S9
Cellular Location:Cell junction, Cell membrane, Multi-pass membrane protein, tight junction
Calculated MW:51kDa/62kDa/64kDa
Observed MW:64kDa-80kDa
Synonyms:MARVELD2, DFNB49, MARVD2, MRVLDC2, Tric
Background:The protein encoded by this gene is a membrane protein found at the tight junctions between epithelial cells. The encoded protein helps establish epithelial barriers such as those in the organ of Corti, where these barriers are required for normal hearing. Defects in this gene are a cause of deafness autosomal recessive type 49 (DFNB49). Two transcript variants encoding different isoforms have been found for this gene.
UniProt Code:Q8N4S9
NCBI GenInfo Identifier:289666784
NCBI Gene ID:153562
NCBI Accession:NP_001033692.2
UniProt Secondary Accession:Q8N4S9,Q96NM9, A1BQX0, A1BQX1, A8KA97,
UniProt Related Accession:Q8N4S9
Molecular Weight:64,168 Da
NCBI Full Name:MARVEL domain-containing protein 2 isoform 1
NCBI Synonym Full Names:MARVEL domain containing 2
NCBI Official Symbol:MARVELD2  
NCBI Official Synonym Symbols:Tric; DFNB49; MARVD2; MRVLDC2  
NCBI Protein Information:MARVEL domain-containing protein 2; tricellulin; MARVEL (membrane-associating) domain containing 2
UniProt Protein Name:MARVEL domain-containing protein 2
UniProt Synonym Protein Names:Tricellulin
UniProt Gene Name:MARVELD2  
UniProt Entry Name:MALD2_HUMAN
Anti-MARVELD2 Antibody (CAB12612)Western blot analysis of extracts of various cell lines, using MARVELD2 antibody (CAB12612) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s.
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