Anti-MARK3 Antibody (CAB19324)
- SKU:
- CAB19324
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CTAK1
- Synonyms:
- KP78
- Synonyms:
- PAR1A
- Synonyms:
- Par-1a
- Synonyms:
- MARK3
Description
| Product Name: | MARK3 Rabbit pAb |
| Product Code: | CAB19324 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | CTAK1, KP78, PAR1A, Par-1a, MARK3 |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human MARK3. |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | Recombinant protein of human MARK3. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 4140 |
| Uniprot: | P27448 |
| Observed MW: | Refer to figures |
| UniProt Protein Function: | MARK3: an ubiquitous serine/threonine kinase of the CAMKL family. Phosphorylates Cdc25C on serine 216 and promotes 14-3-3 protein binding. A positive regulator of Wnt signalling. Ubiquitously expressed in human tissues and cell lines. Seven alternatively spliced isoforms have been reported. |
| UniProt Protein Details: | Protein type:Protein kinase, CAMK; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; CAMK group; CAMKL family; MARK subfamily Chromosomal Location of Human Ortholog: 14q32.32 Cellular Component: plasma membrane Molecular Function:protein serine/threonine kinase activity; protein binding; ATP binding Biological Process: protein amino acid phosphorylation |
| NCBI Summary: | The protein encoded by this gene is activated by phosphorylation and in turn is involved in the phosphorylation of tau proteins MAP2 and MAP4. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
| UniProt Code: | P27448 |
| NCBI GenInfo Identifier: | 341941142 |
| NCBI Gene ID: | 4140 |
| NCBI Accession: | P27448.4 |
| UniProt Secondary Accession: | P27448,O60219, Q86TT8, Q8TB41, Q8WX83, Q96RG1, Q9UMY9 Q9UN34, |
| UniProt Related Accession: | P27448 |
| Molecular Weight: | 74,151 Da |
| NCBI Full Name: | MAP/microtubule affinity-regulating kinase 3 |
| NCBI Synonym Full Names: | MAP/microtubule affinity-regulating kinase 3 |
| NCBI Official Symbol: | MARK3 |
| NCBI Official Synonym Symbols: | KP78; CTAK1; PAR1A; Par-1a |
| NCBI Protein Information: | MAP/microtubule affinity-regulating kinase 3; EMK-2; C-TAK1; ELKL motif kinase 2; protein kinase STK10; ser/Thr protein kinase PAR-1; cdc25C-associated protein kinase 1; serine/threonine-protein kinase p78 |
| UniProt Protein Name: | MAP/microtubule affinity-regulating kinase 3 |
| UniProt Synonym Protein Names: | C-TAK1; cTAK1; Cdc25C-associated protein kinase 1; ELKL motif kinase 2; EMK-2; Protein kinase STK10; Ser/Thr protein kinase PAR-1; Par-1a; Serine/threonine-protein kinase p78 |
| Protein Family: | MAP/microtubule affinity-regulating kinase |
| UniProt Gene Name: | MARK3 |
| UniProt Entry Name: | MARK3_HUMAN |
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