Cell Biology Antibodies 5

Anti-MAGEA11 Antibody (CAB15288)

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SKU:
CAB15288
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-MAGEA11 Antibody
Antibody SKU:CAB15288
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human MAGEA11 (NP_005357.2).
Application:WB
Recommended Dilution:WB 1:200 - 1:2000
Reactivity:Human
Positive Samples:A375, A549, OVCAR3
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human MAGEA11 (NP_005357.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:METQ FRRG GLGC SPAS IKRK KKRE DSGD FGLQ VSTM FSED DFQS TERA PYGP QLQW SQDL PRVQ VFRE QANL EDRS PRRT QRIT GGEQ VLWG PITQ IFPT VRPA DLTR VI
Gene ID:4110
Uniprot:P43364
Cellular Location:Cytoplasm, Nucleus
Calculated MW:44kDa/48kDa
Observed MW:48kDa
Synonyms:MAGEA11, CT1.11, MAGE-11, MAGE11, MAGEA-11
Background:This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Two transcript variants encoding different isoforms have been found for this gene.
UniProt Protein Function:Acts as androgen receptor coregulator that increases androgen receptor activity by modulating the receptors interdomain interaction. May play a role in embryonal development and tumor transformation or aspects of tumor progression.
NCBI Summary:This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Code:P43364
NCBI GenInfo Identifier:61744473
NCBI Gene ID:4110
NCBI Accession:NP_001011544.1
UniProt Secondary Accession:P43364,Q5ETU4, Q6ZRZ5,
UniProt Related Accession:P43364
Molecular Weight:47
NCBI Full Name:melanoma-associated antigen 11 isoform b
NCBI Synonym Full Names:MAGE family member A11
NCBI Official Symbol:MAGEA11  
NCBI Official Synonym Symbols:CT1.11; MAGE11; MAGE-11; MAGEA-11  
NCBI Protein Information:melanoma-associated antigen 11
UniProt Protein Name:Melanoma-associated antigen 11
UniProt Synonym Protein Names:Cancer/testis antigen 1.11; CT1.11; MAGE-11 antigen
UniProt Gene Name:MAGEA11  
Anti-MAGEA11 Antibody (CAB15288)Western blot analysis of extracts of various cell lines, using MAGEA11 antibody (CAB15288) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
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