Anti-MAG Antibody (CAB9671)
- SKU:
- CAB9671
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- GMA
- Synonyms:
- S-MAG
- Synonyms:
- SIGLEC-4A
- Synonyms:
- SIGLEC4A
- Synonyms:
- SPG75
- Research Area:
- Cell Biology
Description
| Product Name: | MAG Rabbit mAb |
| Product Code: | CAB9671 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | GMA, S-MAG, SIGLEC-4A, SIGLEC4A, SPG75 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human MAG |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | SH-SY5Y, Mouse brain, Rat brain |
| Immunogen: | A synthesized peptide derived from human MAG |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 4099 |
| Uniprot: | P20916 |
| Calculated MW: | 100kDa |
| Observed MW: | 100KDa |
| UniProt Protein Function: | MAG: Adhesion molecule in postnatal neural development that mediates sialic-acid dependent cell-cell interactions between neuronal and myelinating cells. Preferentially binds to alpha-2,3- linked sialic acid. Binds to RTN4R. Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cell adhesion; Membrane protein, integral Chromosomal Location of Human Ortholog: 19q13.1 Cellular Component: paranode region of axon; plasma membrane; integral to membrane Molecular Function:carbohydrate binding Biological Process: substantia nigra development; nerve growth factor receptor signaling pathway; negative regulation of axonogenesis; regulation of axonogenesis; cell adhesion; blood coagulation; leukocyte migration |
| NCBI Summary: | The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2010] |
| UniProt Code: | P20916 |
| NCBI GenInfo Identifier: | 126689 |
| NCBI Gene ID: | 4099 |
| NCBI Accession: | P20916.1 |
| UniProt Secondary Accession: | P20916,Q567S4, B7Z2E5, F5GYC0, |
| UniProt Related Accession: | P20916 |
| Molecular Weight: | 66,224 Da |
| NCBI Full Name: | Myelin-associated glycoprotein |
| NCBI Synonym Full Names: | myelin associated glycoprotein |
| NCBI Official Symbol: | MAG |
| NCBI Official Synonym Symbols: | GMA; S-MAG; SIGLEC4A; SIGLEC-4A |
| NCBI Protein Information: | myelin-associated glycoprotein; sialic acid binding Ig-like lectin 4A; sialic acid-binding immunoglobulin-like lectin 4A |
| UniProt Protein Name: | Myelin-associated glycoprotein |
| UniProt Synonym Protein Names: | Siglec-4a |
| Protein Family: | Magainins |
| UniProt Gene Name: | MAG |
| UniProt Entry Name: | MAG_HUMAN |
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