Anti-MAD2L1BP Antibody (CAB19600)
- SKU:
- CAB19600
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CMT2
Description
| Product Name: | MAD2L1BP Rabbit mAb |
| Product Code: | CAB19600 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | CMT2 |
| Applications: | WB, IHC, IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human MAD2L1BP |
| Applications: | WB, IHC, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, HepG2 |
| Immunogen: | A synthesized peptide derived from human MAD2L1BP |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 9587 |
| Uniprot: | Q15013 |
| Calculated MW: | 34kDa |
| Observed MW: | 37KDa |
| UniProt Protein Function: | MAD2L1BP: May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex. Belongs to the MAD2L1BP family.Protein type: Cell cycle regulationChromosomal Location of Human Ortholog: 6p21.1Cellular Component: cytoplasm; nucleusMolecular Function: protein bindingBiological Process: mitotic cell cycle checkpoint; regulation of exit from mitosis |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q15013 |
| NCBI GenInfo Identifier: | 3123048 |
| NCBI Gene ID: | 9587 |
| NCBI Accession: | Q15013.1 |
| UniProt Secondary Accession: | Q15013,Q6IBB1, B4DLV3, E9PAT7 |
| UniProt Related Accession: | Q15013 |
| Molecular Weight: | 34,676 Da |
| NCBI Full Name: | MAD2L1-binding protein |
| NCBI Synonym Full Names: | MAD2L1 binding protein |
| NCBI Official Symbol: | MAD2L1BP |
| NCBI Official Synonym Symbols: | CMT2 |
| NCBI Protein Information: | MAD2L1-binding protein |
| UniProt Protein Name: | MAD2L1-binding protein |
| UniProt Synonym Protein Names: | Caught by MAD2 protein |
| Protein Family: | MAD2L1-binding protein |
| UniProt Gene Name: | MAD2L1BP |
| UniProt Entry Name: | MD2BP_HUMAN |
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