Metabolism Antibodies 3

Anti-LYPLA2 Antibody (CAB15792)

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SKU:
CAB15792
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Metabolism

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-LYPLA2 Antibody
Antibody SKU:CAB15792
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 147-231 of human LYPLA2 (NP_009191.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:293T, HT-29, Raji, Mouse thymus, Mouse brain, Rat lung
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 147-231 of human LYPLA2 (NP_009191.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:CWLP LHRA FPQA ANGS AKDL AILQ CHGE LDPM VPVR FGAL TAEK LRSV VTPA RVQF KTYP GVMH SSCP QEMA AVKE FLEK LLPP V
Gene ID:11313
Uniprot:O95372
Cellular Location:Cytoplasm
Calculated MW:24kDa
Observed MW:25kDa
Synonyms:LYPLA2, APT-2, APT2, DJ886K2.4
Background:Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. There are alternatively spliced transcript variants described for this gene but the full length nature is not known yet.
UniProt Protein Function:LYPLA2: May hydrolyze fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has lysophospholipase activity. Deacylates GAP43. Belongs to the AB hydrolase 2 family.
UniProt Protein Details:

Protein type:Lipid Metabolism - glycerophospholipid; EC 3.1.2.-; Phospholipase

Chromosomal Location of Human Ortholog: 1p36.11

Cellular Component: cytoplasm

Molecular Function:palmitoyl-(protein) hydrolase activity

Biological Process: protein depalmitoylation

NCBI Summary:Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. There are alternatively spliced transcript variants described for this gene but the full length nature is not known yet. [provided by RefSeq, Jul 2008]
UniProt Code:O95372
NCBI GenInfo Identifier:41017276
NCBI Gene ID:11313
NCBI Accession:O95372.1
UniProt Secondary Accession:O95372,Q7Z4Z2,
UniProt Related Accession:O95372
Molecular Weight:24,737 Da
NCBI Full Name:Acyl-protein thioesterase 2
NCBI Synonym Full Names:lysophospholipase II
NCBI Official Symbol:LYPLA2  
NCBI Official Synonym Symbols:APT2; APT-2; DJ886K2.4  
NCBI Protein Information:acyl-protein thioesterase 2
UniProt Protein Name:Acyl-protein thioesterase 2
UniProt Synonym Protein Names:Lysophospholipase II; LPL-II; LysoPLA II
Protein Family:Acyl-protein thioesterase
UniProt Gene Name:LYPLA2  
UniProt Entry Name:LYPA2_HUMAN
Anti-LYPLA2 Antibody (CAB15792)Western blot analysis of extracts of various cell lines, using LYPLA2 antibody (CAB15792) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.
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system_update_altDatasheetHuman LYPLA2 Recombinant Protein Acyl-Protein Thioesterase 2 is a cytoplasmic protein that belongs to the AB Hydrolase 2 family. LYPLA2 is a lysophospholipase and hydrol